Document Detail


A comparative study of lens gamma crystallins using isoelectric focusing.
MedLine Citation:
PMID:  6883995     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The isoelectric points of gamma crystallins of the lenses of rats, dogfish, calves, and humans differ, with a range of pH 8.87-6.80. In each species, one gamma crystallin component with an isoelectric point at pH 7.5 is present, but at differing levels. Amino acid compositions of this component were similar among these four species. All pH 7.5 isoelectric point proteins crossreact immunochemically. A common messenger RNA must be present for this gamma crystallin in all of these species.
Authors:
S Zigman; J Schultz; T Yulo
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Comparative biochemistry and physiology. B, Comparative biochemistry     Volume:  75     ISSN:  0305-0491     ISO Abbreviation:  Comp. Biochem. Physiol., B     Publication Date:  1983  
Date Detail:
Created Date:  1983-10-21     Completed Date:  1983-10-21     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  2984730R     Medline TA:  Comp Biochem Physiol B     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  425-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Amino Acids / isolation & purification
Animals
Cats
Cattle
Chemical Phenomena
Chemistry
Crystallins / genetics,  isolation & purification*
Dogfish
Humans
Isoelectric Focusing
Lens, Crystalline / analysis*
Middle Aged
RNA, Messenger / isolation & purification
Rats
Species Specificity
Grant Support
ID/Acronym/Agency:
EY-00459/EY/NEI NIH HHS
Chemical
Reg. No./Substance:
0/Amino Acids; 0/Crystallins; 0/RNA, Messenger

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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