Document Detail

A comparative study of labor induced by oral prostaglandin E2 and buccal tablets of demoxytocin.
MedLine Citation:
PMID:  42577     Owner:  NLM     Status:  MEDLINE    
A comparative study of the efficacy of oral prostaglandin E2 and buccal tablets of demoxytocin for induction of labor in overdue pregnancies was made in groups of randomly selected patients. Labor was successfully induced in 95.7% of the women in the prostaglandin group and 92.1% of the women in the demoxytocin group. Although the operative delivery rate was low in both groups, it was significantly higher for the demoxytocin group. A low rate of perinatal distress was recorded and there were no serious side effects in either group. The time from start of induction until delivery, as well as the time from amniotomy until delivery, were compared for primiparae and multiparae separately. No significant differences were found. The blood loss during the third stage of labor was lower in the prostaglandin group. We find oral induction of labor in overdue pregnancies effective, safe and convenient.
M Ulstein; N Sagen; S N Eikhom
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  17     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:    1979 Nov-Dec
Date Detail:
Created Date:  1980-03-17     Completed Date:  1980-03-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  243-5     Citation Subset:  IM    
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MeSH Terms
Administration, Oral
Infant, Newborn
Labor, Induced*
Oxytocin / administration & dosage,  analogs & derivatives*
Pregnancy, Prolonged*
Prostaglandins E, Synthetic / administration & dosage*
Reg. No./Substance:
0/Prostaglandins E, Synthetic; 50-56-6/Oxytocin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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