Document Detail

A comparative study on the impact of fresh variables on the success of frozen-thawed embryo transfer cycles using 2PN sibling embryos in women with/without polycystic ovary syndrome.
MedLine Citation:
PMID:  22103769     Owner:  NLM     Status:  Publisher    
Aims: The aim of the present study was to identify the fresh variables that influence the frozen-thawed embryo transfer (FET) outcome using sibling two pronuclei (2PN) embryos in women with polycystic ovary syndrome (PCOS) and non-PCOS women. Material & methods: Fifty-five FET cycles were performed using sibling embryos randomly cryopreserved at 2PN states and basal/cycle characteristics of fresh variables were compared between PCOS and non-PCOS groups according to the success in FET pregnancy: group A (pregnant PCOS); group B (not pregnant PCOS); group C (pregnant non-PCOS); group D (not pregnant non-PCOS). Results: In PCOS patients, higher progesterone level on human chorionic gonadotropin (hCG) day was observed in group A than in group B (0.9 ± 0.0 vs. 0.5 ± 0.3, p = 0.004). In non-PCOS patients who achieved a pregnancy in the fresh cycle, a subsequent FET cycle using sibling 2PN embryos conferred a thirteen times increased chance of achieving pregnancy (OR 13.0; 95% CI, 2.3-74.1). Embryo quality and endometrial maturation were comparable between A and B or C and D. Conclusions: The success of the fresh embryo transfer (ET)was the most important predictor of pregnancy in FET cycles in the non-PCOS group. The relationship between serum progesterone on hCG day in the fresh cycle and the outcome of subsequent FET would benefit further evaluation in PCOS group.
Hye Jun Lee; Seung-Yup Ku; Seok Hyun Kim; Young Min Choi; Jung Gu Kim; Shin Yong Moon
Related Documents :
2737359 - Components of change in adolescent fertility, 1971-1979.
24497859 - Association between air pollution and preterm birth among neonates born in isfahan, iran.
7183039 - Obstetric problems in the adolescent zambian mother studied at the university teaching ...
9110059 - Observations of stillbirths, birthweight and maternal haemoglobin in teenage pregnancy ...
18155029 - Environmental injustice: childhood lead poisoning, teen pregnancy, and tobacco.
9763159 - Delayed first pregnancy among african-american adolescent smokers.
9263069 - Relationships of light and heavy fetuses to uterine position, placental weight, gestati...
16920249 - A randomized comparison of side effects and patient convenience between cyclogest suppo...
18091359 - Fetal onset of general movements.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-21
Journal Detail:
Title:  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology     Volume:  -     ISSN:  1473-0766     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807913     Medline TA:  Gynecol Endocrinol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Obstetrics and Gynecology, College of Medicine , Seoul , Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Coupled-Channels Quantum Theory of Electronic Flux Density in Electronically Adiabatic Processes: Fu...
Next Document:  Role of oral tranexamic acid in melasma patients treated with IPL and low fluence QS Nd:YAG laser.