Document Detail

A comparative study of helical-type and traditional-type artery bypass grafts: numerical simulation.
MedLine Citation:
PMID:  21869617     Owner:  NLM     Status:  In-Data-Review    
Preliminary studies on an individual helical graft indicated that its hemodynamics might be improved while pressure drop increased compared with a traditional graft. Aiming to investigate whether the benefits of a helical graft to hemodynamics dominate its deficits, this study numerically carried out comparative study of helical-type artery bypass graft (ABG) and traditional-type ABG under both steady and pulsatile flow conditions. The results showed that a helical-type ABG resulted in reduced oscillating shear index, improved wall shear stress, enhanced flow mixing and three-dimensionality, and improved flow behavior at the distal anastomosis and occluded section of the host vessel compared with traditional-type ABG. More important, although a helical-type ABG did increase the pressure drop compared with a traditional one, its maximum percentage increase during a cardiac cycle was <21% which is still within physiological sense. Therefore, we believe that the adoption of helical bypass could help to prevent intimal hyperplasia (IH) and thrombosis at the distal anastomosis and improve the graft patency while keeping clinical maintenance. This investigation provided an important basis for the clinical applications and theory support of helical graft.
Jun Wen; Tinghui Zheng; Wentao Jiang; Xiaoyan Deng; Yubo Fan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  ASAIO journal (American Society for Artificial Internal Organs : 1992)     Volume:  57     ISSN:  1538-943X     ISO Abbreviation:  ASAIO J.     Publication Date:    2011 Sep-Oct
Date Detail:
Created Date:  2011-08-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204109     Medline TA:  ASAIO J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  399-406     Citation Subset:  IM    
From the *Department of Applied Mechanics, Sichuan University, Chengdu; and †School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
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