| A comparative study of the biological properties of Australian elapid venoms. | |
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MedLine Citation:
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PMID: 1981349 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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1. The hemorrhagic, procoagulant, anticoagulant, protease, phosphodiesterase, alkaline phosphomonoesterase, L-amino acid oxidase, acetylcholinesterase, arginine ester hydrolase, phospholipase A, 5'-nucleotidase and hyaluronidase activities of 39 samples of venoms from 13 species (15 taxa) of Australian elapids were determined and the Sephadex G-75 gel filtration patterns for some of the venoms were also examined. 2. The results indicate that Australian elapid venoms can be divided into two groups: procoagulant Australian venoms (including N. scutatus, N. ater, O. scutellatus, O. microlepidotus, P. porphyriacus, T. carinatus, H. stephensii and P. textilis) and non-procoagulant Australian venoms (including A. superbus, P. colletti, P. australis, P. guttatus and A. antarcticus). 3. The non-procoagulant Australian venoms exhibited biological properties similar to other elapid venoms, while the procoagulant Australian venoms exhibited some properties characteristic of viperid venoms. 4. The data show that information on venom biological properties can be used for differentiation of many species of Australian elapids. 5. Particularly useful for this purpose are the hyaluronidase, alkaline phosphomonoesterase, acetylcholinesterase, and the procoagulant activities and the Sephadex G-75 gel filtration patterns of the venoms. |
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Authors:
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N H Tan; G Ponnudurai |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology Volume: 97 ISSN: 0742-8413 ISO Abbreviation: Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. Publication Date: 1990 |
Date Detail:
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Created Date: 1991-04-09 Completed Date: 1991-04-09 Revised Date: 2007-07-23 |
Medline Journal Info:
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Nlm Unique ID: 8310013 Medline TA: Comp Biochem Physiol C Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 99-106 Citation Subset: IM |
Affiliation:
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Department of Biochemistry, University of Malaya, Kuala Lumpur. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Australia Chromatography, Gel Elapid Venoms / isolation & purification, metabolism, pharmacology, toxicity* Hydrolases / isolation & purification, metabolism Snakes Species Specificity |
| Chemical | |
Reg. No./Substance:
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0/Elapid Venoms; EC 3.-/Hydrolases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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