Document Detail

A comparative study of the acute antihypertensive effect of Adalat capsules and Corinfar dragées, two different nifedipine preparations.
MedLine Citation:
PMID:  3391034     Owner:  NLM     Status:  MEDLINE    
The calcium entry blocker nifedipine produces systemic vasodilation and decreases the elevated vascular resistance in hypertensive patients. The authors investigated the acute antihypertensive effect of sublingually administered nifedipine in two different formulas: Adalat capsules and Corinfar dragées. There was no significant difference between both these formulas regarding their effects on blood pressure and heart rate, and their side effects were also similar. The authors conclude that the acute antihypertensive effect of nifedipine, either in capsules or in dragées, is equipotent in essential hypertension.
I Kiss; C Farsang
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Cor et vasa     Volume:  30     ISSN:  0010-8650     ISO Abbreviation:  Cor Vasa     Publication Date:  1988  
Date Detail:
Created Date:  1988-08-19     Completed Date:  1988-08-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372614     Medline TA:  Cor Vasa     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  105-9     Citation Subset:  IM    
2nd Department of Internal Medicine, Semmelweis Medical University, Budapest, Hungary.
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MeSH Terms
Administration, Oral
Blood Pressure / drug effects
Heart Rate / drug effects
Hypertension / drug therapy*
Middle Aged
Nifedipine / administration & dosage*,  therapeutic use
Time Factors
Reg. No./Substance:
0/Capsules; 21829-25-4/Nifedipine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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