| A comparative study of Japanese and British BCG vaccine strains in newborn infants. | |
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MedLine Citation:
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PMID: 2655676 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A prospective study on the British and Japanese BCG vaccines in newborn infants was carried out in which 317 and 285 infants were randomly allocated and vaccinated with the British and Japanese BCG vaccines, respectively. Four follow-up examinations were carried out with an average of 98% of the study cohort attending all sessions. About half the infants did not produce any visible response at the end of the first week. All, by the end of the third month, had characteristic BCG scars with an average diameter of 4.6 mm. A Mantoux test was carried out at six months. A mean skin induration of 7.2 mm (SD 5.3 mm) was recorded. Significantly higher proportions of infants given Japanese BCG were found to be tuberculin convertors (74.7%) when compared to those given British BCG (51.4%). Breast-feeding practices and the mothers' tuberculin status did not influence markedly their infants response to tuberculin. |
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Authors:
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T E Goh; M Low; C H Chen; T H Tan |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Asia-Pacific journal of public health / Asia-Pacific Academic Consortium for Public Health Volume: 3 ISSN: 1010-5395 ISO Abbreviation: Asia Pac J Public Health Publication Date: 1989 |
Date Detail:
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Created Date: 1989-07-12 Completed Date: 1989-07-12 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8708538 Medline TA: Asia Pac J Public Health Country: HONG KONG |
Other Details:
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Languages: eng Pagination: 32-40 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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BCG Vaccine* Child Child, Preschool Clinical Trials as Topic Double-Blind Method Female Great Britain Humans Infant Infant, Newborn Japan Male Prospective Studies Random Allocation Singapore Tuberculin Test Tuberculosis / immunology, prevention & control* |
| Chemical | |
Reg. No./Substance:
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0/BCG Vaccine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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