Document Detail


The comparative role of consanguinity in infant and childhood mortality in Pakistan.
MedLine Citation:
PMID:  9177121     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
As part of the 1990/1991 Pakistan Demographic and Health Survey, data were collected on the outcome of 26,408 births to 6,611 women, with mortality rates investigated at specific age intervals during the first 5 years of life. Bivariate and multivariate logistic regression analyses were employed to examine the comparative roles of consanguineous marriage and a number of demographic and socioeconomic factors, including the sex of the child, maternal age, maternal education, birth interval and birth order, as determinants of early death. The results indicate that, even after controlling for these non-genetic variables, inbreeding at the level of first cousin exerted a significant adverse effect on survival in four of the five age intervals examined, neonatal, post-neonatal, infant and under 5 years.
Authors:
J C Grant; A H Bittles
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Annals of human genetics     Volume:  61     ISSN:  0003-4800     ISO Abbreviation:  Ann. Hum. Genet.     Publication Date:  1997 Mar 
Date Detail:
Created Date:  1997-07-23     Completed Date:  1997-07-23     Revised Date:  2009-09-29    
Medline Journal Info:
Nlm Unique ID:  0416661     Medline TA:  Ann Hum Genet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  143-9     Citation Subset:  IM    
Affiliation:
King's College, University of London, U.K.
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MeSH Terms
Descriptor/Qualifier:
Child, Preschool
Consanguinity*
Female
Humans
Infant
Infant Mortality*
Infant, Newborn
Mortality
Odds Ratio
Pakistan / epidemiology
Regression Analysis
Grant Support
ID/Acronym/Agency:
//Wellcome Trust

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