Document Detail


The comparative anatomy of islets.
MedLine Citation:
PMID:  20217492     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the past 20 years, numerous publications on a variety of mammalian and non-mammalian species have appeared in the literature to supplement the excellent comparative work performed in the 70s and 80s by the Falkmer, Epple, and Youson groups. What emerges is that islets are much more complex than once thought and show a lot of similarities in rodents and higher primates. The diversity of lifestyles, metabolic demands, and diets has most likely influenced the great diversity in both structure and cell-type content of islets in lower vertebrate species. In this chapter, I try to provide an overview of the evolution from endocrine cell types in invertebrates to the higher mammals and focus on what has been reported in the literature and some of our own experiences and also include a description of other hormones reported to be found in islets.
Authors:
R Scott Heller
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Advances in experimental medicine and biology     Volume:  654     ISSN:  0065-2598     ISO Abbreviation:  Adv. Exp. Med. Biol.     Publication Date:  2010  
Date Detail:
Created Date:  2010-03-10     Completed Date:  2010-06-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0121103     Medline TA:  Adv Exp Med Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  21-37     Citation Subset:  IM    
Affiliation:
Hagedorn Research Institute, Department of Beta Cell Regeneration, Gentofte DK2820, Denmark. shll@hagedorn.dk
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MeSH Terms
Descriptor/Qualifier:
Anatomy, Comparative / methods*
Animals
Endocrine System
Evolution
Hormones / metabolism
Humans
Invertebrates / physiology
Islets of Langerhans / anatomy & histology*,  physiology*
Models, Anatomic
Models, Biological
Phylogeny
Species Specificity
Vertebrates / physiology
Chemical
Reg. No./Substance:
0/Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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