| A commentary on clinical trials in chronic heart failure. | |
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MedLine Citation:
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PMID: 16959759 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Heart failure is a common condition and becoming more common. Many treatments have been evaluated in large clinical trials during the last few decades. These trials can be criticized but do provide an evidence base for treatment, probably greater than for most other clinical conditions. Weaknesses exist in relation to age, ejection fraction, and gender. Most trials have included patients 10 years younger than those in the general population. There is little evidence for efficacy in patients with a near normal ejection fraction. Few women have been included in trials. |
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Authors:
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Philip A Poole-Wilson; Alexander R Lyon; Adam M Jacques |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Seminars in cardiothoracic and vascular anesthesia Volume: 10 ISSN: 1089-2532 ISO Abbreviation: Semin Cardiothorac Vasc Anesth Publication Date: 2006 Sep |
Date Detail:
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Created Date: 2006-09-08 Completed Date: 2007-01-10 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9807630 Medline TA: Semin Cardiothorac Vasc Anesth Country: United States |
Other Details:
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Languages: eng Pagination: 242-5 Citation Subset: IM |
Affiliation:
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Department of Cardiac Medicine, National Heart & Lung Institute, Imperial College London, London, United Kingdom. p.poole-wilson@imperial.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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therapeutic use Angiotensin II Type 1 Receptor Blockers / therapeutic use Angiotensin-Converting Enzyme Inhibitors / therapeutic use Clinical Trials as Topic Diuretics / therapeutic use Heart Failure / drug therapy*, epidemiology Humans |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Angiotensin II Type 1 Receptor Blockers; 0/Angiotensin-Converting Enzyme Inhibitors; 0/Diuretics |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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