| A combined treatment with D-amino acids and electroacupuncture produces a greater analgesia than either treatment alone; naloxone reverses these effects. | |
| | |
MedLine Citation:
|
PMID: 7402686 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The D-amino acids (DAA), D-phenylalanine and D-leucine, produce naloxone reversible analgesia; electroacupuncture (EA) also produces analgesia which is blocked by naloxone. Combining the two treatments produces an additive effect with a larger analgesia than that produced by either treatment given alone; this combined effect is also blocked by naloxone. Moreover only 62% of the mice show EA analgesia and 53% show D-amino acid (DAA) analgesia; 80% of the animals show marked analgesia with both EA plus DAA treatment. Perhaps the combination of EA with DAA will provide a potent method for the treatment of clinical pain. |
| | |
Authors:
|
R S Cheng; B Pomeranz |
Related Documents
:
|
15050876 - Awareness of folic acid for prevention of neural tube defects in a community with high ... 18570426 - A novel method for the synthesis of cellulose nanofibril whiskers from banana fibers an... 5762396 - Polymethacrylic acid: effects on lymphocyte output of the thoracic duct in rats. 12848626 - Bioavailability of oral vs. subcutaneous low-dose methotrexate in patients with crohn's... 10614596 - Neurochemical changes following postmortem ischemia in the rat retina. 15194656 - Gastro-oesophageal reflux monitoring: review and consensus report on detection and defi... |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Pain Volume: 8 ISSN: 0304-3959 ISO Abbreviation: Pain Publication Date: 1980 Apr |
Date Detail:
|
Created Date: 1980-10-27 Completed Date: 1980-10-27 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7508686 Medline TA: Pain Country: NETHERLANDS |
Other Details:
|
Languages: eng Pagination: 231-6 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acupuncture Therapy* Analgesia* Animals Electric Stimulation Female Leucine / therapeutic use* Mice Naloxone / pharmacology Pain / therapy Phenylalanine / therapeutic use* |
| Chemical | |
Reg. No./Substance:
|
465-65-6/Naloxone; 61-90-5/Leucine; 63-91-2/Phenylalanine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: An experimental evaluation of auricular diagnosis: the somatotopic mapping or musculoskeletal pain a...
Next Document: Antinociceptive effect of peripheral segmental electrical stimulation in the rat.