| A combination of oral cabergoline and double cloprostenol injections to produce third-quarter gestation termination in the bitch. | |
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MedLine Citation:
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PMID: 16960040 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To assess the efficacy and safety of a combined cabergoline and cloprostenol protocol to terminate third-quarter pregnancy, 22 pregnant bitches that ranged from 35 to 45 days after mating were randomly assigned to a treatment group (n=13) or to an untreated control group (n=9). The animals were monitored for 12 days, and pregnancy termination was confirmed by ultrasound examination. Twelve of the 13 treated bitches aborted within 9 days of the initiation of treatment (mean 4.6 days). Only mild side effects were observed. The control animals had normal gestational courses, as did the bitch that did not respond to the therapy. This combination of drugs appeared to be a practical, safe, and efficient abortifacient when used in third-quarter pregnancies. |
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Authors:
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Yanina Corrada; Raúl Rodríguez; Mariana Tortora; Daniel Arias; Cristina Gobello |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Journal of the American Animal Hospital Association Volume: 42 ISSN: 1547-3317 ISO Abbreviation: J Am Anim Hosp Assoc Publication Date: 2006 Sep-Oct |
Date Detail:
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Created Date: 2006-09-08 Completed Date: 2008-07-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0415027 Medline TA: J Am Anim Hosp Assoc Country: United States |
Other Details:
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Languages: eng Pagination: 366-70 Citation Subset: IM |
Affiliation:
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Imaging Diagnosis Service, Faculty of Veterinary Medicine, National University of La Plata, La Plata, Argentina. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortifacient Agents
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administration & dosage* Abortion, Induced / methods, veterinary* Abortion, Veterinary / chemically induced* Administration, Oral Animals Cloprostenol / administration & dosage Dogs Dopamine Agonists / administration & dosage Drug Therapy, Combination Ergolines / administration & dosage Female Injections, Subcutaneous / veterinary Luteolytic Agents / administration & dosage Pregnancy Pregnancy Outcome |
| Chemical | |
Reg. No./Substance:
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0/Abortifacient Agents; 0/Dopamine Agonists; 0/Ergolines; 0/Luteolytic Agents; 40665-92-7/Cloprostenol; 81409-90-7/cabergoline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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