Document Detail


The combination of fibrin glue and quilting reduces drainage in the extended latissimus dorsi flap donor site.
MedLine Citation:
PMID:  20517084     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The use of quilting sutures in the extended latissimus dorsi flap donor site significantly reduces the incidence of donor-site seroma. However, the donor site has a drain inserted, and the duration of use of this drain often dictates when a patient is discharged to home from the hospital. Fibrin glue has been shown to reduce the need for drainage at other operative sites. The authors therefore evaluated the use of fibrin glue (Tisseel Lyo; Baxter Healthcare, Norfolk, United Kingdom) in addition to quilting in reducing the total volume and duration of drainage following extended latissimus dorsi flap breast reconstruction.
METHODS: The authors compared a group of 11 consecutive, prospective patients who underwent extended latissimus dorsi donor-site closure with fibrin glue and quilting with a control group of 24 consecutive, retrospective patients who underwent extended latissimus dorsi donor-site closed with quilting alone.
RESULTS: The results show that the combination of fibrin glue and quilting in the extended latissimus dorsi flap donor site significantly reduces average drainage in the immediate postoperative period: 13 ml compared with 170 ml (p <or= 0.001); average total drainage, 330 ml compared with 645 ml (p = 0.018); and average drain stay, 4 days compared with 5 days (p = 0.022).
CONCLUSION: Fibrin glue potentially may reduce the numbers of days that drains are left in situ or even reduce the drainage to such a degree that drains are no longer necessary for patients undergoing extended latissimus dorsi-based breast reconstructions.
Authors:
Syed N Ali; Parneet Gill; Dimitrios Oikonomou; Guy D Sterne
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Plastic and reconstructive surgery     Volume:  125     ISSN:  1529-4242     ISO Abbreviation:  Plast. Reconstr. Surg.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-02     Completed Date:  2010-06-18     Revised Date:  2011-02-16    
Medline Journal Info:
Nlm Unique ID:  1306050     Medline TA:  Plast Reconstr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1615-9     Citation Subset:  AIM; IM    
Affiliation:
Department of Plastic and Reconstructive Surgery, Sandwell and West Birmingham NHS Trust, City Hospital, Birmingham, UK. mrnadir@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Drainage
Female
Fibrin Tissue Adhesive / therapeutic use*
Follow-Up Studies
Humans
Mammaplasty / methods*
Middle Aged
Muscle, Skeletal / surgery
Postoperative Complications / prevention & control*
Prospective Studies
Seroma / prevention & control
Surgical Flaps*
Suture Techniques*
Tissue Adhesives / therapeutic use*
Chemical
Reg. No./Substance:
0/Fibrin Tissue Adhesive; 0/Tissue Adhesives

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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