Document Detail

A cognitive model for schizophrenia and its possible neural basis.
MedLine Citation:
PMID:  7879648     Owner:  NLM     Status:  MEDLINE    
It is proposed that the basic disturbance in schizophrenia corresponds to a disruption of the normal relationship between stored material and current sensory input. The link between information processing disturbances and their biological bases may be facilitated by the use of paradigms derived from animal learning theory. A model for the emergence of schizophrenic symptoms is presented. The core cognitive abnormality may result from a disturbance at any point in the neural circuit involved in the prediction of subsequent sensory input.
D R Hemsley
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta psychiatrica Scandinavica. Supplementum     Volume:  384     ISSN:  0065-1591     ISO Abbreviation:  Acta Psychiatr Scand Suppl     Publication Date:  1994  
Date Detail:
Created Date:  1995-03-31     Completed Date:  1995-03-31     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  0370365     Medline TA:  Acta Psychiatr Scand Suppl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  80-6     Citation Subset:  IM    
Department of Psychology, Institute of Psychiatry, London, United Kingdom.
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MeSH Terms
Brain / physiopathology*
Cognition Disorders / etiology*
Schizophrenia / complications*,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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