Document Detail

A coagulopathy of the owl monkey (Aotus trivirgatus) associated with high antithrombin III activity.
MedLine Citation:
PMID:  828226     Owner:  NLM     Status:  MEDLINE    
The species-associated coagulopathy of the owl monkey (Aotus trivirgatus) was shown to be caused by a high level of circulating anticoagulant, antithrombin III, in approximately 4-6 times the activity in which the same anticoagulant is found in man or the rhesus monkey (Macaca mulatta). The survival of the owl monkey in the presence of this added biological risk is an interesting and enigmatic observation. Treatment with protamine, prednisone, or estradiol did not alter the activity of circulating anticoagulant.
W F Loeb; J L Cicmanec; M Wickum
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Laboratory animal science     Volume:  26     ISSN:  0023-6764     ISO Abbreviation:  Lab. Anim. Sci.     Publication Date:  1976 Dec 
Date Detail:
Created Date:  1977-04-30     Completed Date:  1977-04-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1266503     Medline TA:  Lab Anim Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1084-7     Citation Subset:  IM    
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MeSH Terms
Antithrombins / blood*
Aotus trivirgatus / blood*
Blood Coagulation Disorders / blood,  veterinary*
Blood Coagulation Tests
Haplorhini / blood*
Macaca mulatta / blood
Monkey Diseases / blood*
Prothrombin Time
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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