| The co-occurrence of serologically proven myasthenia gravis and Miller Fisher/Guillain Barré overlap syndrome: a case report. | |
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MedLine Citation:
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PMID: 18804791 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The co-occurrence of myasthenia gravis (MG) and Guillain Barré syndrome (GBS) is uncommon with a few reported cases in the literature. There is only one reported case of MG and Miller Fisher variant of GBS. We described an 84 year old Chinese woman with underlying seropositive myasthenia gravis (MG) who presented with ophthalmoplegia, areflexia and acute neuromuscular weakness. She was proved to have co-occurrence of MG and GBS/Miller Fisher overlap syndrome with positive anti-GQ1b antibody. The unusual finding in this patient raises an interesting question on their pathogenesis with the possibility that prior activation of the immune system may predispose the development of autoantibodies against other antigens within the same set of muscles. |
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Authors:
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Kwok Kwong Lau; Khean Jin Goh; Han Chih Hencher Lee; Yuk Tat Eric Chan; Chong Tin Tan |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-09-19 |
Journal Detail:
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Title: Journal of the neurological sciences Volume: 276 ISSN: 0022-510X ISO Abbreviation: J. Neurol. Sci. Publication Date: 2009 Jan |
Date Detail:
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Created Date: 2009-01-12 Completed Date: 2009-03-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: Netherlands |
Other Details:
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Languages: eng Pagination: 187-8 Citation Subset: IM |
Affiliation:
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Department of Medicine and Geriatrics, Princess Margaret Hospital, Kwai Chung, New Territories, Hong Kong. dominickklau@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged, 80 and over Antibodies / blood Female Gangliosides / immunology Guillain-Barre Syndrome / complications*, immunology* Humans Myasthenia Gravis / complications*, immunology* Serologic Tests / methods* |
| Chemical | |
Reg. No./Substance:
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0/Antibodies; 0/Gangliosides; 68652-37-9/GQ1b ganglioside |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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