| A co-housing strategy to improve fecundity of mice in timed matings. | |
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MedLine Citation:
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PMID: 23340789 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Timed matings of mice are often carried out to obtain offspring of a precise age when required for a study. Timed matings involve housing male and female mice together for a limited time period, typically overnight. A limitation of this practice is that many mouse pairs fail to mate during the brief co-housing period. The authors co-housed each breeding pair in the same cage but separated by a transparent partition for 3 d before carrying out timed matings. This co-housing strategy resulted in increased copulation during the timed mating period and also significantly increased the average number of pups produced per breeding pair. The authors suggest that co-housing likely permits male urine-borne pheromones to induce female estrus and also enables the expression of male and female mating behaviors. |
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Authors:
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Robert J Stiles; Adam G Schrum; Diana Gil |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Lab animal Volume: 42 ISSN: 1548-4475 ISO Abbreviation: Lab Anim (NY) Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-01-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0417737 Medline TA: Lab Anim (NY) Country: United States |
Other Details:
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Languages: eng Pagination: 62-5 Citation Subset: IM |
Affiliation:
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Department of Immunology, College of Medicine, Mayo Clinic, Rochester, Minnesota, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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