Document Detail


Chitosan/poly(DL,lactide-co-glycolide) scaffolds for tissue engineering.
MedLine Citation:
PMID:  22960878     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Chitosan/poly(DL-lactide-co-glycolide) (Ch/DL PLG) composite scaffolds were fabricated by freeze-drying lyophilization, and were evaluated and compared for use as a bone regeneration scaffold through measurements of the compression mechanical properties of the porous scaffolds. Also, In vitro cell culture of Sprague-Dawley rat's osteoblasts were used to evaluate the phenotype expression of cells in the scaffolds, characterizing the cellular adhesion, proliferation and alkaline phosphatase activity. The gene expression of osteocalcin, sialoprotein, alkaline phosphatase, Type I collagen and TGFβ1 were confirmed in the samples; moreover, it was confirmed, the mineralization by IR spectra and EDS analysis. Our results thus show that Ch/DL PLG scaffolds are suitable for biological applications.
Authors:
S A Martel-Estrada; I Olivas-Armendáriz; C A Martínez-Pérez; T Hernández; E I Acosta-Gómez; J G Chacón-Nava; F Jiménez-Vega; P E García-Casillas
Related Documents :
23680108 - Expression and activity of recombinant proaerolysin derived from aeromonas hydrophila c...
3022918 - Presence of chromosomal abnormalities and lack of aids retrovirus dna sequences in aids...
23538758 - Early gene and protein expression associated with osteoblast differentiation in respons...
24101108 - Effect of endothelin inhibition on lung fibroblasts on patients with systemic sclerosis.
16689868 - Microbial oxidation of 1,2-dichloroethane under anoxic conditions with nitrate as elect...
22115788 - Methods suitable for high-throughput screening of sirnas and other chemical compounds w...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-9
Journal Detail:
Title:  Journal of materials science. Materials in medicine     Volume:  -     ISSN:  1573-4838     ISO Abbreviation:  J Mater Sci Mater Med     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9013087     Medline TA:  J Mater Sci Mater Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Instituto de Ingeniería y Tecnología, Universidad Autónoma de Cd. Juárez, Av. Del Charro 450 Norte, Col. Partido Romero, 32310, Cd. Juárez, CHIH, Mexico, mizul@yahoo.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Successful eradication of a FVIII inhibitor in a 60-year-old patient with mild haemophilia A using s...
Next Document:  Inaccuracy of age assessment from images of postpubescent subjects in cases of alleged child pornogr...