Document Detail

Chitosan/poly(DL,lactide-co-glycolide) scaffolds for tissue engineering.
MedLine Citation:
PMID:  22960878     Owner:  NLM     Status:  Publisher    
Chitosan/poly(DL-lactide-co-glycolide) (Ch/DL PLG) composite scaffolds were fabricated by freeze-drying lyophilization, and were evaluated and compared for use as a bone regeneration scaffold through measurements of the compression mechanical properties of the porous scaffolds. Also, In vitro cell culture of Sprague-Dawley rat's osteoblasts were used to evaluate the phenotype expression of cells in the scaffolds, characterizing the cellular adhesion, proliferation and alkaline phosphatase activity. The gene expression of osteocalcin, sialoprotein, alkaline phosphatase, Type I collagen and TGFβ1 were confirmed in the samples; moreover, it was confirmed, the mineralization by IR spectra and EDS analysis. Our results thus show that Ch/DL PLG scaffolds are suitable for biological applications.
S A Martel-Estrada; I Olivas-Armendáriz; C A Martínez-Pérez; T Hernández; E I Acosta-Gómez; J G Chacón-Nava; F Jiménez-Vega; P E García-Casillas
Related Documents :
5473898 - Cellular control of the synthesis and activity of the bacterial luminescent system.
24024338 - Effect of tangnaikang on tgf-beta1-induced transdifferentiation of human renal tubular ...
25026698 - Induced production of new diterpenoids in the fungus penicillium funiculosum.
6170648 - Small nuclear rnas in cellular growth and differentiation. i: metabolic alterations see...
12628828 - A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue...
17641858 - Inhibitory effect of curcumin on proliferation of human pterygium fibroblasts.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-9
Journal Detail:
Title:  Journal of materials science. Materials in medicine     Volume:  -     ISSN:  1573-4838     ISO Abbreviation:  J Mater Sci Mater Med     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9013087     Medline TA:  J Mater Sci Mater Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Instituto de Ingeniería y Tecnología, Universidad Autónoma de Cd. Juárez, Av. Del Charro 450 Norte, Col. Partido Romero, 32310, Cd. Juárez, CHIH, Mexico,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Successful eradication of a FVIII inhibitor in a 60-year-old patient with mild haemophilia A using s...
Next Document:  Inaccuracy of age assessment from images of postpubescent subjects in cases of alleged child pornogr...