Document Detail


A clinicopathological survey of gallstones in the autopsy population.
MedLine Citation:
PMID:  8263858     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This prospective study looked at the autopsy prevalence of gallstones and their relationship with symptoms and gallbladder pathology. Fifty consecutive autopsies were selected. The gallbladder was examined macroscopically and microscopically and gallstones were examined, cut and classified. Four females at autopsy had had previous cholecystectomies. Thirty three percent of patients had gallstones at post-mortem with a male to female ratio of 1:1.24. Histological features of the gallbladders were: normal 39.1%, cholecystitis 37.0%, hypertrophy 8.7% and fibrosis 15.2%. Increasing age was significantly associated with increasing common bile duct (CBD) circumference. Muscle hypertrophy and fibrosis may represent part of a spectrum of "burnt out" gallbladder disease. Fifteen percent of autopsy patients had calcular cholecystitis but were asymptomatic and the reason for this is unclear.
Authors:
R Heames; C du Boulay
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Royal Naval Medical Service     Volume:  79     ISSN:  0035-9033     ISO Abbreviation:  J R Nav Med Serv     Publication Date:  1993  
Date Detail:
Created Date:  1994-01-21     Completed Date:  1994-01-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503111     Medline TA:  J R Nav Med Serv     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  83-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Autopsy
Cholelithiasis / epidemiology*,  pathology
Female
Gallbladder / pathology
Humans
Male
Middle Aged
Prevalence
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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