Document Detail

A clinicopathological study of 323 patients with oligodendrogliomas.
MedLine Citation:
PMID:  3947035     Owner:  NLM     Status:  MEDLINE    
All patients with oligodendrogliomas (554) from the repository of the Armed Forces Institute of Pathology were retrospectively analyzed. The pathological diagnosis was confirmed in 323 patients and each case was graded according to a previously established grading system. The clinical features of these 323 verified cases of oligodendroglioma are presented, analyzed, and compared with findings in previous studies. There is a significant age skew according to tumor grade, with 68% of patients with grade A tumors under 40 years and 83% of patients with grade D tumors over 40 years of age. Headache was the most common symptom, followed by seizure, visual loss, papilledema, paralysis, and dementia. No symptoms showed a statistically significant correlation with tumor grade. However, tumor grading allowed significant prognostic statements to be made. Attention is drawn to several often neglected symptoms of oligodendrogliomas: ataxia, hemorrhage, stroke, and cerebrospinal fluid spread. This is, to our knowledge, the largest clinicopathological study of oligodendrogliomas to date.
C L Ludwig; M T Smith; A D Godfrey; V W Armbrustmacher
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of neurology     Volume:  19     ISSN:  0364-5134     ISO Abbreviation:  Ann. Neurol.     Publication Date:  1986 Jan 
Date Detail:
Created Date:  1986-03-11     Completed Date:  1986-03-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7707449     Medline TA:  Ann Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  15-21     Citation Subset:  IM    
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MeSH Terms
Brain Neoplasms / mortality,  pathology*,  radiography,  therapy
Child, Preschool
Combined Modality Therapy
Infant, Newborn
Middle Aged
Oligodendroglioma / mortality,  pathology*,  radiography,  therapy
Time Factors

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