Document Detail

The clinician's responsibility in relation to DVLA guidance.
MedLine Citation:
PMID:  22041619     Owner:  NLM     Status:  In-Data-Review    
for cardiovascular risk with particular attention paid to the QT interval on the ECG. They advise that all patients being considered for methadone treatment, should undergo careful evaluation for any history of syncope or palpitations. Physical examination, and echocardiography when indicated (particularly in those patients on high doses of >=100mls/day; history of heart disease; family history of sudden cardiac death) should exclude any underlying structural heart disease. These patients should have an ECG performed before commencing therapy, at 30 days and then annually. The effects of QT prolongation have been clearly shown to be dose related with methadone.
Stephen Hill
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acute medicine     Volume:  10     ISSN:  1747-4892     ISO Abbreviation:  Acute Med     Publication Date:  2011  
Date Detail:
Created Date:  2011-11-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101553725     Medline TA:  Acute Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  110     Citation Subset:  IM    
Consultant Physician in Acute Medicine Medical Assessment Unit Queen Alexandra Hospital Portsmouth PO6 3LY.
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