Document Detail

The clinician-investigator: unavoidable but manageable tension.
MedLine Citation:
PMID:  15049297     Owner:  KIE     Status:  MEDLINE    
The "difference position" holds that clinical research and therapeutic medical practice are sufficiently distinct activities to require different ethical rules and principles. The "similarity position" holds instead that clinical investigators ought to be bound by the same fundamental principles that govern therapeutic medicine--specifically, a duty to provide the optimal therapeutic benefit to each patient or subject. Some defenders of the similarity position defend it because of the overlap between the role of attending physician and the role of investigator in a research trial. This overlap is maximal when the same physician occupies both roles with respect to a particular patient-subject. We address the ethical tensions inherent in that role conflict and argue that the tensions are real but manageable. The difference position provides a sound ethical framework within which to manage those tensions, while the similarity position is unsatisfactory because it seeks to deny the existence of the tensions.
Howard Brody; Franklin G Miller
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Kennedy Institute of Ethics journal     Volume:  13     ISSN:  1054-6863     ISO Abbreviation:  Kennedy Inst Ethics J     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2004-03-29     Completed Date:  2004-05-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9109135     Medline TA:  Kennedy Inst Ethics J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  329-46     Citation Subset:  E    
Center for Ethics and Humanities in the Life Sciences, Michigan State University, East Lansing, Michigan, USA.
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MeSH Terms
Conflict of Interest*
Controlled Clinical Trials as Topic / ethics*
Ethics, Medical
Ethics, Research*
Informed Consent
Moral Obligations
Physician-Patient Relations
Physicians / ethics*
Practice Guidelines as Topic
Professional Role*
Quality Assurance, Health Care
Research Design
Research Personnel / ethics*
Researcher-Subject Relations / ethics
Therapeutic Human Experimentation / ethics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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