| A clinical trial of Gingkco Biloba Extract in patients with intermittent claudication. | |
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MedLine Citation:
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PMID: 2254678 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirty-seven patients with stage 2 peripheral vascular disease were randomised to receive a six month course of Gingkco Biloba Extract (Tanakan) or matching placebo. Assessment, by claudication distance, A/B ratio, Doppler ankle pressure response to exercise together with recovery time, and a 10 cm analogue scale (LAS) estimation of maximal pain severity, was performed before treatment, and at 6, 12 and 24 weeks. LAS scores were significantly improved after 24 weeks in patients receiving EgB, but not placebo. Claudication distance was significantly increased by Egb. Although claudication distance also increased in the placebo group, this was not significant. A/B ratio and Doppler ankle responses to exercise did not show any significant change in either group at any time interval, nor did the post exercise recovery time. Gingkco Biloba Extract is a safe and effective method of improving walking distance and reducing pain severity in patients with intermittent claudication, although Doppler studies have failed to suggest any gross improvement in the perfusion of the ischaemic leg. |
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Authors:
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G J Thomson; R K Vohra; M H Carr; M G Walker |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International angiology : a journal of the International Union of Angiology Volume: 9 ISSN: 0392-9590 ISO Abbreviation: Int Angiol Publication Date: 1990 Apr-Jun |
Date Detail:
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Created Date: 1991-01-24 Completed Date: 1991-01-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8402693 Medline TA: Int Angiol Country: ITALY |
Other Details:
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Languages: eng Pagination: 75-8 Citation Subset: IM |
Affiliation:
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Department of Vascular Surgery, Manchester Royal Infirmary, G.B. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Double-Blind Method Ginkgo biloba Humans Intermittent Claudication / drug therapy*, ultrasonography Plant Extracts / therapeutic use* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Ginkgo biloba extract 761; 0/Plant Extracts |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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