| A clinical study of patients with and without recurrence of paroxysmal atrial fibrillation after pulmonary vein isolation. | |
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MedLine Citation:
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PMID: 15683535 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Patients with paroxysmal atrial fibrillation (PAF) can be treated by pulmonary vein (PV) isolation. However, the recurrence rate after this procedure is relatively high. We sought to evaluate the quality of life (QOL) of patients with PAF recurrence after PV isolation and to analyze factors related to recurrences. Seventy-two drug-refractory PAF patients (59 men, 13 women, mean age 52 +/- 10) were included. PV isolation was based on the disappearance of PV potentials recorded from a Lasso catheter after segmental ostium ablation. Automatic foci were observed in 47 patients (65.3%) during the procedure. A mean of 3.1 +/- 0.9 PVs was isolated. Patients were followed for a mean of 10.3 +/- 5.1 months, during which 27 experienced >1 episode of PAF. QOL was scored from 0 (situation before ablation) to 10 (no episode after ablation) based on a questionnaire completed by 69 patients (95.8%). QOL was judged very good in 26 patients (none with PAF recurrences), better in 30 (15 with PAF recurrences), unchanged in 11 (10 with recurrences), and worse in 2 patients with PAF recurrences. Longer histories of PAF and a lower percentage of patients with automatic foci identified during the procedure were observed in the group with, than in the group without recurrences (P < 0.05). PV isolation improved QOL in patients with PAF, including in patients with recurrences. The length of PAF history and observation of automatic foci may be of importance for recurrences of PAF during long-term follow-up. |
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Authors:
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Jian Chen; Per Ivar Hoff; Knut Ståle Erga; Ole Rossvoll; Ole-Jørgen Ohm |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 28 Suppl 1 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2005-02-01 Completed Date: 2005-06-03 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: United States |
Other Details:
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Languages: eng Pagination: S86-9 Citation Subset: IM |
Affiliation:
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Institute of Medicine and Department of Heart Disease, Haukeland University Hospital, University of Bergen, Norway. jian.chen@med.uib.no |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Atrial Fibrillation
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surgery* Catheter Ablation* Female Humans Male Middle Aged Pulmonary Veins / surgery* Quality of Life* Recurrence Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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