Document Detail

A clinical study of patients with pemphigus vulgaris and pemphigus foliaceous: an 11-year retrospective study (1996-2006).
MedLine Citation:
PMID:  18627388     Owner:  NLM     Status:  MEDLINE    
Only a few reports have been published of detailed clinical studies of pemphigus in Japan. The aim of this study was to determine the clinical characteristics of patients with pemphigus vulgaris (PV) and pemphigus foliaceous (PF), who were newly diagnosed in the dermatology department of Kurume University Hospital, Japan, over the past 11 years. The primary site of involvement was the oral mucosa in 21 patients (75%) with PV. At the initial visit, most of the patients with PV had moderate to severe disease. With regard to management, systemic corticosteroids were the mainstay of treatment for patients with PV, and plasmapheresis was the most frequently used adjuvant therapy. Dapsone was the mainstay of treatment for the patients with PF. The patients were investigated for any association with an underlying malignancy; in patients with PV, lung, stomach and uterine cancers (one patient each) were seen.
N Ishii; Y Maeyama; T Karashima; T Nakama; M Kusuhara; S Yasumoto; T Hashimoto
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Publication Detail:
Type:  Journal Article     Date:  2008-07-08
Journal Detail:
Title:  Clinical and experimental dermatology     Volume:  33     ISSN:  1365-2230     ISO Abbreviation:  Clin. Exp. Dermatol.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-09-19     Completed Date:  2008-12-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7606847     Medline TA:  Clin Exp Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  641-3     Citation Subset:  IM    
Department of Dermatology, Kurume University School of Medicine, Kurume, Japan.
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MeSH Terms
Adrenal Cortex Hormones / therapeutic use
Anti-Infective Agents / therapeutic use
Dapsone / therapeutic use
Diagnosis, Differential
Japan / epidemiology
Middle Aged
Pemphigus* / drug therapy,  epidemiology,  pathology
Retrospective Studies
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Anti-Infective Agents; 80-08-0/Dapsone

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