Document Detail


The clinical significance of placental villous edema.
MedLine Citation:
PMID:  6682216     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A study was undertaken to determine why there is such variability in morbidity and mortality in neonates exposed to antenatal chorioamnionitis. Villous edema provides a clue. It was present in 72/83 placentas with chorioamnionitis. The extent and severity of the edema had a strong, positive correlation with cord arterial blood pH values, low Apgar scores, the need to resuscitate vigorously at birth, the subsequent need for assisted ventilation, the frequency of hyaline membrane disease, and neonatal mortality. Most of the difference in morbidity and mortality between preterm and full-term infants was related to the greater severity and extent of villous edema in those born prematurely.
Authors:
R L Naeye; M J Maisels; R P Lorenz; J J Botti
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Pediatrics     Volume:  71     ISSN:  0031-4005     ISO Abbreviation:  Pediatrics     Publication Date:  1983 Apr 
Date Detail:
Created Date:  1983-05-05     Completed Date:  1983-05-05     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  588-94     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Amnion
Apgar Score
Chorion
Chorionic Villi* / pathology
Edema / complications*,  pathology
Female
Fetal Blood
Fetal Hypoxia / etiology*
Humans
Hydrogen-Ion Concentration
Infant Mortality
Infant, Newborn
Infant, Newborn, Diseases / etiology
Inflammation / complications
Placenta* / pathology
Placenta Diseases / complications,  pathology
Pregnancy
Grant Support
ID/Acronym/Agency:
1-R01-N S-16403-02//PHS HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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