| The clinical significance of ABO blood group incompatibility. | |
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MedLine Citation:
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PMID: 8252149 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To compare incidence, severity, and treatment of jaundice in ABO-compatible and -incompatible infants. DESIGN: Retrospective chart review. SETTING: A 340-bed acute-care public and teaching hospital. PATIENTS OR OTHER PARTICIPANTS: All infants with blood groups A or B delivered in 1990 by Rh-positive mothers with blood group O. On direct antiglobulin testing 65 infants had positive and 78 had negative results. The control group comprised 78 infants with blood group O born to mothers of blood group O. INTERVENTION: None. RESULTS: Infants who were ABO-incompatible and showed positive results to the direct antiglobulin test had the highest incidence of jaundice and underwent more tests and phototherapy. Infants who showed negative results to the direct antiglobulin test had jaundice incidence rates between those seen for control infants and infants who tested positive. Mean peak bilirubin levels did not differ significantly among the groups. CONCLUSION: Incompatibility of ABO blood group is associated with an increased incidence of jaundice and higher phototherapy rates. Clinicians should continue to be concerned about possible ABO incompatibility in infants with jaundice born to mothers with blood group O. |
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Authors:
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D J Madlon-Kay |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Archives of family medicine Volume: 2 ISSN: 1063-3987 ISO Abbreviation: Arch Fam Med Publication Date: 1993 Mar |
Date Detail:
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Created Date: 1994-01-13 Completed Date: 1994-01-13 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9300357 Medline TA: Arch Fam Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 285-7 Citation Subset: IM |
Affiliation:
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Department of Family Medicine, St Paul, Minn-Ramsey Medical Center. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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ABO Blood-Group System* Age Factors Bilirubin / blood Blood Group Incompatibility / complications* Female Humans Hyperbilirubinemia / blood, diagnosis, etiology, therapy Incidence Infant, Newborn Isoantigens / blood Jaundice / blood, diagnosis, etiology*, therapy Male Phototherapy Pregnancy Rh-Hr Blood-Group System |
| Chemical | |
Reg. No./Substance:
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0/ABO Blood-Group System; 0/Isoantigens; 0/Rh-Hr Blood-Group System; 635-65-4/Bilirubin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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