Document Detail


The clinical relevance of fetal variant of the circle of willis and its influence on the cerebral collateral circulation.
MedLine Citation:
PMID:  22315173     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
In a fetal variation of circle of Willis (CoW) there is an embryological defect of the primary collateral circulation. Besides the fact that collateral flow cannot develop between anterior and posterior circulation, the tentorium namely prevents cerebellar vessels from connecting to the supra-tentorium territory. Therefore patients with a fetal variation of circle of Willis could be more prone to develop vascular insufficiency. An association between the regional cerebral blood volume (rCBV) inter-hemispheric asymmetry and CoW collateralization was observed with a topographic significance of corona radiate rather than centrum semiovale. An overview of the literature is given. We propose a fetal variation of circle of Willis as a risk factor for stroke should be subject of further investigation.
Authors:
Hung-Ming Wu; Yu-Ming Chuang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurologica Taiwanica     Volume:  20     ISSN:  1028-768X     ISO Abbreviation:  Acta Neurol Taiwan     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2012-02-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815355     Medline TA:  Acta Neurol Taiwan     Country:  China (Republic : 1949- )    
Other Details:
Languages:  eng     Pagination:  232-142     Citation Subset:  IM    
Affiliation:
Departmemt of Neurology, Far-Eastern Memorial Hospital.
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