Document Detail


A clinical and radiological evaluation of DFDBA with amniotic membrane versus bovine derived xenograft with amniotic membrane in human periodontal grade II furcation defects.
MedLine Citation:
PMID:  19277899     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of the present study was to clinically and radiographically evaluate and compare the efficacy of demineralized freeze dried bone allograft (DFDBA) and bovine derived xenogenic bone graft (BDX) [Bio-Oss] with amniotic membrane (AM) as guided tissue regeneration (GTR) in the treatment of human periodontal Grade II buccal furcation defects. Ten patients suffering from chronic periodontitis, displaying bilateral Grade II buccal furcation defect, were randomly treated using DFDBA with AM (Experimental site A) or using bovine derived xenograft (BDX) with AM (Experimental site B). The clinical and radiographic parameters were recorded at baseline, 6 and 9 months. Healing was uneventful in all patients except one site which was treated with BDX + AM. At 9 months after therapy, soft tissue measurements for the DFDBA + AM group showed pocket depth (PD) reduction of 4.7 mm +/- 0.58, and relative attachment level gain of 4.8 mm + 0.32, while the BDX + AM group showed a PD reduction of 4.4 mm +/- 0.27, and AL gain of 5.1 mm +/- 0.09. Osseous measurements showed bone fill of 2.1 mm +/- 0.36 for the DFDBA + AM group and 2.43 mm +/- 0.38 for the BDX + AM group. Percentage gain in bone was 76.3% for the DFDBA + AM group and 79.6% for the BDX + AM group. Statistical analysis revealed there was no statistical difference between the two materials in all measurements. Within the limits of the present study, it can be concluded that: (1) at 9 months after surgery both therapies resulted in significant PD reductions and CAL gains and (2) significant improvement was seen in bone fill and percentage gain with both the material, however, there was no significant difference between both.
Authors:
Shaila V Kothiwale; P Anuroopa; A L Gajiwala
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2009-03-10
Journal Detail:
Title:  Cell and tissue banking     Volume:  10     ISSN:  1573-6814     ISO Abbreviation:  Cell Tissue Bank     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-06     Completed Date:  2010-01-27     Revised Date:  2010-03-03    
Medline Journal Info:
Nlm Unique ID:  100965121     Medline TA:  Cell Tissue Bank     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  317-26     Citation Subset:  IM    
Affiliation:
Department of Periodontics, KLE'S VK Institute of Dental Sciences, Belgaum, Karnataka, India. shailakothiwale2000@yahoo.co.in
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MeSH Terms
Descriptor/Qualifier:
Adult
Amnion / transplantation*
Animals
Bone Substitutes / therapeutic use*
Bone Transplantation / methods
Cattle
Female
Furcation Defects / diagnosis,  surgery*
Guided Tissue Regeneration, Periodontal / methods*
Humans
Male
Middle Aged
Minerals / therapeutic use*
Radiology
Transplantation, Heterologous*
Transplantation, Homologous*
Chemical
Reg. No./Substance:
0/Bio-Oss; 0/Bone Substitutes; 0/Minerals

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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