Document Detail

A clinical and radiological evaluation of DFDBA with amniotic membrane versus bovine derived xenograft with amniotic membrane in human periodontal grade II furcation defects.
MedLine Citation:
PMID:  19277899     Owner:  NLM     Status:  MEDLINE    
The purpose of the present study was to clinically and radiographically evaluate and compare the efficacy of demineralized freeze dried bone allograft (DFDBA) and bovine derived xenogenic bone graft (BDX) [Bio-Oss] with amniotic membrane (AM) as guided tissue regeneration (GTR) in the treatment of human periodontal Grade II buccal furcation defects. Ten patients suffering from chronic periodontitis, displaying bilateral Grade II buccal furcation defect, were randomly treated using DFDBA with AM (Experimental site A) or using bovine derived xenograft (BDX) with AM (Experimental site B). The clinical and radiographic parameters were recorded at baseline, 6 and 9 months. Healing was uneventful in all patients except one site which was treated with BDX + AM. At 9 months after therapy, soft tissue measurements for the DFDBA + AM group showed pocket depth (PD) reduction of 4.7 mm +/- 0.58, and relative attachment level gain of 4.8 mm + 0.32, while the BDX + AM group showed a PD reduction of 4.4 mm +/- 0.27, and AL gain of 5.1 mm +/- 0.09. Osseous measurements showed bone fill of 2.1 mm +/- 0.36 for the DFDBA + AM group and 2.43 mm +/- 0.38 for the BDX + AM group. Percentage gain in bone was 76.3% for the DFDBA + AM group and 79.6% for the BDX + AM group. Statistical analysis revealed there was no statistical difference between the two materials in all measurements. Within the limits of the present study, it can be concluded that: (1) at 9 months after surgery both therapies resulted in significant PD reductions and CAL gains and (2) significant improvement was seen in bone fill and percentage gain with both the material, however, there was no significant difference between both.
Shaila V Kothiwale; P Anuroopa; A L Gajiwala
Related Documents :
1920009 - The use of sustained release delivery of chlorhexidine for the maintenance of periodont...
9763329 - Evaluation of tetracycline fiber therapy with digital image analysis.
19478489 - Prevention of preterm delivery with periodontal treatment.
21873349 - Clinical outcomes after endovascular treatment of superficial femoral disease in patien...
20367089 - Root-coverage procedures for the treatment of localized recession-type defects: a cochr...
25346499 - Rationale and design of triple axel: trial for early anticoagulation in acute ischemic ...
23652299 - An effective treatment for penile strangulation.
22873699 - Do traumatic brain contusions increase in size after decompressive craniectomy?
3735569 - The natural history of microsurgical lymphovenous anastomoses: an experimental study.
Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2009-03-10
Journal Detail:
Title:  Cell and tissue banking     Volume:  10     ISSN:  1573-6814     ISO Abbreviation:  Cell Tissue Bank     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-06     Completed Date:  2010-01-27     Revised Date:  2010-03-03    
Medline Journal Info:
Nlm Unique ID:  100965121     Medline TA:  Cell Tissue Bank     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  317-26     Citation Subset:  IM    
Department of Periodontics, KLE'S VK Institute of Dental Sciences, Belgaum, Karnataka, India.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amnion / transplantation*
Bone Substitutes / therapeutic use*
Bone Transplantation / methods
Furcation Defects / diagnosis,  surgery*
Guided Tissue Regeneration, Periodontal / methods*
Middle Aged
Minerals / therapeutic use*
Transplantation, Heterologous*
Transplantation, Homologous*
Reg. No./Substance:
0/Bio-Oss; 0/Bone Substitutes; 0/Minerals

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The construct validity of the Health Utilities Index Mark 3 in assessing mental health in population...
Next Document:  Changes in lipid distribution during aging and its modulation by calorie restriction.