Document Detail

The clinical, quality of life, and economic consequences of chronic anemia and transfusion support in patients with myelodysplastic syndromes.
MedLine Citation:
PMID:  22300879     Owner:  NLM     Status:  Publisher    
Most patients with myelodysplastic syndromes (MDS) require transfusions due to chronic anemia. Apart from the acute risks associated with transfusions, chronic anemia and red blood cell (RBC) transfusion dependence impact negatively on survival and quality of life (QoL), and are associated with iron overload, potentially leading to organ damage. QoL studies demonstrate that regular transfusions do not correct the impact of chronic anemia. Furthermore, chronic transfusion support requires substantial resources. Therefore, major goals are to prevent or effectively treat anemia. Indeed, innovative drugs have been shown to be effective in achieving transfusion independence by altering the natural course of MDS.
Uwe Platzbecker; Lorenz C Hofbauer; Gerhard Ehninger; Kristina Hölig
Related Documents :
24184499 - Bow hunter's syndrome causing vertebrobasilar insufficiency in a young male with neck m...
22421409 - Evaluation of dysplasia through detailed cytomorphology in 3156 patients from the düsse...
22315189 - Call for change in prenatal counseling for down syndrome.
24859509 - Neonatal diagnosis of a patient with hypoparathyroidism, sensorineural deafness and ren...
22373669 - Mortality of inherited arrhythmia syndromes; insight into their natural history.
22615039 - Abdominal compartment syndrome due to a giant multilobulated ovarian serous cystadenoma...
7778599 - Multiple congenital malformations in two sibs reminiscent of hydrolethalus and pseudotr...
23224909 - Potential role of taurine in the prevention of diabetes and metabolic syndrome.
18296009 - Gradenigo's syndrome.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-31
Journal Detail:
Title:  Leukemia research     Volume:  -     ISSN:  1873-5835     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-2-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7706787     Medline TA:  Leuk Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
University Hospital "Carl Gustav Carus", Medical Clinic and Polyclinic I, Dresden, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Opa1 is essential for retinal ganglion cell synaptic architecture and connectivity.
Next Document:  The multiple-lemma representation of Italian compound nouns: A single case study of deep dyslexia.