Document Detail

The clinical problem of occult cardiac amyloidosis. Forensic implications.
MedLine Citation:
PMID:  1476128     Owner:  NLM     Status:  MEDLINE    
A 68-year-old man with known coronary heart disease experienced rapidly progressive cardiac dysfunction and was found to have occult cardiac amyloidosis at autopsy. The amyloidosis was undiagnosed during life and initially at autopsy. Marked diffuse involvement of the intramural coronary arteries by amyloid deposits resulted in severe luminal compromise of numerous medium and small vessels. The myocardium proper was virtually spared from amyloid deposits. Amyloid-related coronary narrowing contributed to cardiac ischemia and sudden death. The significance of amyloid coronary disease in this patient relates primarily to the difficulty in considering the diagnosis when other reasons for cardiac signs and symptoms preexist. Also, the adverse effects of amyloid coronary disease may be profound without direct myocardial involvement.
E C Petersen; J A Engel; S J Radio; T M Canfield; B M McManus
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of forensic medicine and pathology     Volume:  13     ISSN:  0195-7910     ISO Abbreviation:  Am J Forensic Med Pathol     Publication Date:  1992 Sep 
Date Detail:
Created Date:  1993-02-04     Completed Date:  1993-02-04     Revised Date:  2011-02-02    
Medline Journal Info:
Nlm Unique ID:  8108948     Medline TA:  Am J Forensic Med Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  225-9     Citation Subset:  IM    
Cardiovascular Registry, University of Nebraska Medical Center, Omaha 68198-6495.
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MeSH Terms
Amyloidosis / complications,  pathology*
Cardiomyopathies / complications,  pathology*
Coronary Artery Disease / complications*,  diagnosis
Diagnosis, Differential

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