Document Detail

The clinical picture presented by premature neonates infected with the respiratory syncytial virus.
MedLine Citation:
PMID:  8582403     Owner:  NLM     Status:  MEDLINE    
During the course of a 3-year epidemic of respiratory syncytial virus (RSV) in an Neonatal Intensive Care Unit, we examined premature neonates for the clinical features of RSV infections and the risk factors predisposing towards transmission of the disease. Seventy-nine infants with a median gestational age of 31 weeks were tested in 113 episodes of clinical deterioration for the presence of RSV antigen in nasopharyngeal secretions. Forty-seven results were positive and 66 negative. Bradycardia, which is gestational-age dependent, was the main presenting clinical symptom of an RSV infection in 75% of cases. The probability of an RSV-positive result in an episode with bradycardia, hypercapnia and fever was calculated to be 0.75. The only identifiable epidemiological risk factor was the total number of symptomatic RSV-infected infants in the ward. CONCLUSION. Bradycardia may indicate the presence of an RSV infection: the appropriate tests should be carried out and infection control reinforced immediately.
J Forster; R F Schumacher
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of pediatrics     Volume:  154     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1996-03-21     Completed Date:  1996-03-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  901-5     Citation Subset:  IM    
Universitäts-Kinderklinik, Freiburg, Germany.
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MeSH Terms
Antigens, Viral / analysis
Bradycardia / etiology
Cross Infection / prevention & control
Gestational Age
Hypercapnia / etiology
Infant, Newborn
Infant, Premature, Diseases / physiopathology*
Intensive Care Units, Neonatal
Respiratory Syncytial Virus Infections / physiopathology*,  transmission
Respiratory Syncytial Viruses / immunology
Risk Factors
Reg. No./Substance:
0/Antigens, Viral

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