Document Detail

The clinical importance of axillary lymphadenopathy detected on screening mammography: revisited.
MedLine Citation:
PMID:  15642295     Owner:  NLM     Status:  MEDLINE    
AIM: The aim of this study was to re-evaluate our protocol for the management of isolated axillary lymphadenopathy (ALP) on mammographic screening. METHODS: In a retrospective review of 200,716 women screened at the South West London Breast Screening Service (SWLBSS) over 7 years, 72 women with ALP with an otherwise normal mammogram were identified. Thirteen patients were not recalled, nine of who had a known underlying diagnosis and the remainder had longstanding unchanged mammograms. Fifty-nine patients were recalled for further clinical assessment and investigations, including ultrasound, further mammographic views, fine-needle aspiration cytology (FNAC), blood tests and a chest radiograph. Those with a definite diagnosis were referred for appropriate management and those with benign reactive cytology on FNAC reviewed at 6 weeks with subsequent referral for excision of persisting abnormal nodes. RESULTS: The ultimate diagnosis was benign in 45 cases: 26 benign reactive changes, 11 arthritides, five with dermatological and viral conditions and three with tuberculosis. Malignancy was diagnosed in 13 cases: four with metastatic breast carcinoma and nine with lymphoma/leukaemia. The total number of newly diagnosed malignancies was 20% of women recalled. Another 5% of patients had active tuberculosis. Of the 22 patients with benign reactive cytology, one had significant pathology on excision biopsy: tuberculosis. Over 95% of the results from excision biopsy in these patients did not alter management. CONCLUSION: In the majority of patients, the FNAC results were representative of the final excision pathology. The present study suggests that excision biopsy could be omitted for those patients whose FNAC and culture are negative.
T Patel; R M Given-Wilson; V Thomas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical radiology     Volume:  60     ISSN:  0009-9260     ISO Abbreviation:  Clin Radiol     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-01-11     Completed Date:  2005-03-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1306016     Medline TA:  Clin Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  64-71     Citation Subset:  IM    
St George's Hospital NHSBSP National Training Centre, Duchess of Kent Breast Screening Unit, St George's Hospital, Tooting, London, UK.
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MeSH Terms
Breast Diseases / radiography*
Health Surveys
Lymph Nodes / radiography*
Lymphatic Diseases / radiography*
Mammography / methods*
Middle Aged
Retrospective Studies

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