| The clinical impact of fetal magnetic resonance imaging on management of CNS anomalies in the second trimester of pregnancy. | |
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MedLine Citation:
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PMID: 21080900 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: to evaluate the additional information of second trimester magnetic resonance imaging (MRI) compared to ultrasound in fetuses with identified or suspected central nervous system (CNS) anomalies and to study the clinical impact of the information on pregnancy management. DESIGN: prospective study during 2004-2007. The fetal MRI examination was planned to be performed within 3 days after the ultrasound. Setting. Uppsala University hospital. MATERIAL: twenty-nine pregnant women in whom second trimester ultrasound identified or suspected fetal CNS anomalies. MAIN OUTCOME MEASURES: evaluation of the additional information gained from MRI and the consequence it had on pregnancy management. RESULTS: the mean interval between ultrasound and MRI was 1.6 days (range 0-7). In 16 fetuses (55%), MRI verified the ultrasound diagnosis but provided no additional information, while in 10 (35%) MRI gave additional information without changing the management. In 3 (10%), MRI provided additional information that changed the management of the pregnancy. Two of these women were obese. CONCLUSIONS: fetal MRI in the second trimester might be a clinically valuable adjunct to ultrasound for the evaluation of CNS anomalies, especially when ultrasound is inconclusive due to maternal obesity. |
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Authors:
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Hashem Amini; Ove Axelsson; Marie Raiend; Johan Wikström |
Publication Detail:
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Type: Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Acta obstetricia et gynecologica Scandinavica Volume: 89 ISSN: 1600-0412 ISO Abbreviation: Acta Obstet Gynecol Scand Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-18 Completed Date: 2010-12-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370343 Medline TA: Acta Obstet Gynecol Scand Country: England |
Other Details:
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Languages: eng Pagination: 1571-81 Citation Subset: IM |
Affiliation:
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Department of Women's and Children's Health, Uppsala University, Sweden. Hashem.Amini@kbh.uu.se |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Autopsy Central Nervous System / abnormalities*, pathology Cohort Studies Female Fetal Mortality Fetus / abnormalities Humans Magnetic Resonance Imaging / methods* Nervous System Malformations / diagnosis*, mortality Pregnancy Pregnancy Trimester, Second Prenatal Diagnosis / methods* Prospective Studies Sensitivity and Specificity Sweden Ultrasonography, Prenatal Young Adult |
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