Document Detail

The clinical impact of expert pathological review on lymphoma management: a regional experience.
MedLine Citation:
PMID:  14617006     Owner:  NLM     Status:  MEDLINE    
The All Wales Lymphoma Panel (AWLP) was established in January 1998 to provide a central expert pathological review service for district general hospital pathologists. A discordance rate of 20% between the submitted and reviewed diagnosis has previously been identified. It has not been known whether this change in diagnosis affects clinical management. Ninety-nine patients whose diagnosis was changed as a result of central pathological review are presented. Between January 1998 and August 2000, 125 of 745 (17%) specimens submitted for AWLP review had a consequent change in pathological diagnosis. Of these 125 specimens, 99 (79%) complete case notes were recovered. In all 99 cases, a hypothetical management plan was generated using collected data, clinical protocols and the submitted pathological diagnosis. These plans were compared with the actual management patients received based on the reviewed diagnosis proffered by the AWLP. Forty-six of 99 (46%) cases had a change in management as a result of central pathological review. Overall, management was changed in 8% of cases referred for central pathological review. In conclusion, expert central pathological review has a direct effect on patient management.
Jason F Lester; Stefan D Dojcinov; Richard L Attanoos; Ciaran J O'Brien; Tim S Maughan; Elizabeth T Toy; Chris H Poynton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of haematology     Volume:  123     ISSN:  0007-1048     ISO Abbreviation:  Br. J. Haematol.     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2003-11-17     Completed Date:  2003-12-04     Revised Date:  2006-04-24    
Medline Journal Info:
Nlm Unique ID:  0372544     Medline TA:  Br J Haematol     Country:  England    
Other Details:
Languages:  eng     Pagination:  463-8     Citation Subset:  IM    
Velindre Hospital NHS Trust, Cardiff, UK.
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MeSH Terms
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Diagnosis, Differential
Lymphoma / drug therapy*,  pathology*,  radiotherapy
Middle Aged
Pathology, Surgical*
Patient Care Planning*
Peer Review*

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