| The clinical features of adult unilateral moyamoya disease: does it have the same clinical characteristics as typical moyamoya disease? | |
| | |
MedLine Citation:
|
PMID: 18648196 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The cerebral hemodynamics in unilateral moyamoya disease have not been clarified. The present study was done to clarify the clinical characteristics of patients with unilateral moyamoya disease compared to those with typical moyamoya disease or occlusive lesions of the internal carotid artery, terminal portion or middle cerebral artery. METHODS: We retrospectively analyzed patients who had unilateral or bilateral steno-occlusive lesions at the internal carotid artery terminal portion or proximal middle cerebral artery. We divided the patients into 3 groups: typical moyamoya (n = 25), unilateral moyamoya (n = 12) and nonmoyamoya (n = 44). Atherosclerotic risk factors and frequency of ischemic and hemorrhagic stroke were compared among the 3 groups. We also examined the extent of cerebral collateral vessels by angiography and used single-photon emission computed tomography to measure the regional cerebral blood flow (rCBF) at rest and after acetazolamide injection. RESULTS: The data on age, sex, hyperlipidemia and smoking habits in the unilateral moyamoya group fell in between those of the typical moyamoya and nonmoyamoya groups. Stroke was less frequent in the unilateral moyamoya group compared to the typical moyamoya or nonmoyamoya groups (p < 0.05). The rCBF at rest and after acetazolamide injection were significantly higher in the unilateral moyamoya group than in the typical moyamoya and nonmoyamoya groups (p < 0.05). CONCLUSIONS: Patients with unilateral moyamoya disease appear to have the lowest frequency of stroke and a reduced rCBF, despite the fact that they have more atherosclerotic risk factors than patients with bilateral lesions. |
| | |
Authors:
|
Toshiyasu Ogata; Masahiro Yasaka; Tooru Inoue; Kotaro Yasumori; Setsuro Ibayashi; Mitsuo Iida; Yasushi Okada |
Related Documents
:
|
12791896 - Ischemic stroke and splenic rupture in a case of streptococcus bovis endocarditis. 9378896 - Cerebral hemodynamics and metabolism during infant cardiac surgery. mechanisms of injur... 20847316 - Increased blood-brain barrier permeability on perfusion ct might predict malignant midd... 2230846 - Fatal or severely disabling cerebral infarction during hospitalization for stroke or tr... 11270756 - Measurement of cardiac troponin i levels in the emergency department: predictive value ... 18722186 - Assessment and key targets for therapy in the post-myocardial infarction patient with l... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2008-07-23 |
Journal Detail:
|
Title: Cerebrovascular diseases (Basel, Switzerland) Volume: 26 ISSN: 1421-9786 ISO Abbreviation: Cerebrovasc. Dis. Publication Date: 2008 |
Date Detail:
|
Created Date: 2008-09-10 Completed Date: 2008-12-10 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9100851 Medline TA: Cerebrovasc Dis Country: Switzerland |
Other Details:
|
Languages: eng Pagination: 244-9 Citation Subset: IM |
Copyright Information:
|
Copyright 2008 S. Karger AG, Basel. |
Affiliation:
|
Departments of Cerebrovascular Disease, Cerebrovascular Center and Clinical Research Institute, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan. togata@kyumed.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Angiography, Digital Subtraction Carotid Artery, Internal* / pathology, physiopathology Carotid Stenosis* / complications, pathology, physiopathology Cerebral Angiography Cerebrovascular Circulation* Collateral Circulation Female Humans Infarction, Middle Cerebral Artery* / complications, pathology, physiopathology Male Middle Aged Middle Cerebral Artery* / pathology, physiopathology Moyamoya Disease* / complications, pathology, physiopathology Retrospective Studies Risk Factors Stroke / etiology*, pathology, physiopathology Tomography, Emission-Computed, Single-Photon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Mood disorders after stroke: diagnostic validation of the poststroke depression rating scale.
Next Document: Long-term survival after ischemic stroke in postmenopausal women is affected by an interaction betwe...