Document Detail


The clinical content of preconception care: the use of medications and supplements among women of reproductive age.
MedLine Citation:
PMID:  19081432     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The use of prescription and over-the-counter medications and dietary supplements are common among women of reproductive age. For medications, little information about the teratogenic risks or safety is available, as pregnant women are traditionally excluded from clinical trials, and premarketing animal studies do not necessarily predict the effects of treatment in human pregnancy. Even less is typically known about the effects of dietary supplements on pregnancy outcomes, as they are not held to the same rigorous safety and efficacy standards as prescription medications. Congenital anomalies associated with medication use are potentially preventable, because they are linked with modifiable maternal exposures during the period of organogenesis. However, as women of reproductive age experience acute and chronic conditions that can result in adverse outcomes for the woman and her offspring, the benefits of use of a particular medication before or early in pregnancy may outweigh the risks. Resources and principles outlined in this article will aid healthcare providers in selecting appropriate medication regimens for women of reproductive age, particularly those with chronic health conditions, those who are planning a pregnancy, and those who may become pregnant.
Authors:
Anne L Dunlop; Paula M Gardiner; Cynthia S Shellhaas; M Kathryn Menard; Melissa A McDiarmid
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  199     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-16     Completed Date:  2009-01-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S367-72     Citation Subset:  AIM; IM    
Affiliation:
Department of Family and Preventive Medicine, Emory University School of Medicine, Atlanta, GA, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Dietary Supplements / adverse effects*
Female
Humans
Maternal Welfare
Nonprescription Drugs / adverse effects
Pharmaceutical Preparations / adverse effects*
Preconception Care*
Pregnancy
Pregnancy Outcome
Teratogens
Women's Health
Chemical
Reg. No./Substance:
0/Nonprescription Drugs; 0/Pharmaceutical Preparations; 0/Teratogens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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