| The clinical characteristics of pulmonary alveolar proteinosis: experience at Seoul National University Hospital, and review of the literature. | |
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MedLine Citation:
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PMID: 10331561 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pulmonary alveolar proteinosis is such an extremely rare disease in Korea, that only a few cases have been reported. Meanwhile five cases were experienced at Seoul National University Hospital over ten years since 1987. We summarized the clinical characteristics and courses of them. Seven cases reported in the literature were included to add data about clinical characteristics and courses although only a few case reports mentioned patient's course. Middle aged male patients were mainly affected. No association with particular environmental or occupational exposure was identified. Dyspnea on exertion was the main symptom. Bilateral crackles were consistent, and bilateral parahilar hazy infiltrations on plain chest radiograph and ground glass opacity on high-resolution CT were characteristic. Superimposed infection was not identified in any patient at the time of diagnosis. Decreased diffusing capacity and hypoxia were present in almost every case. Whole lung lavage proved to be an effective therapeutic measure. The response to treatment was good. Long-term course of the disease, e.g. recurrence rate, is not yet known. |
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Authors:
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G Kim; S J Lee; H P Lee; C G Yoo; S K Han; Y S Shim; Y W Kim |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Journal of Korean medical science Volume: 14 ISSN: 1011-8934 ISO Abbreviation: J. Korean Med. Sci. Publication Date: 1999 Apr |
Date Detail:
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Created Date: 1999-07-19 Completed Date: 1999-07-19 Revised Date: 2011-03-16 |
Medline Journal Info:
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Nlm Unique ID: 8703518 Medline TA: J Korean Med Sci Country: KOREA (SOUTH) |
Other Details:
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Languages: eng Pagination: 159-64 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Seoul National University College of Medicine and Lung Institute, SNUMRC, Korea. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Distribution Aged Female Hospitals, Public* Hospitals, University* Humans Korea Male Middle Aged Pulmonary Alveolar Proteinosis / diagnosis, physiopathology*, radiography, therapy Sex Distribution Smoking / adverse effects |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
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Journal Information Journal ID (nlm-ta): J Korean Med Sci Journal ID (pmc): jkms ISSN: 1011-8934 ISSN: 1598-6357 Publisher: Korean Academy of Medical Sciences |
Article Information Download PDF  Print publication date: Month: 4 Year: 1999 Volume: 14 Issue: 2 First Page: 159 Last Page: 164 ID: 3054359 PubMed Id: 10331561 |
| The clinical characteristics of pulmonary alveolar proteinosis: experience at Seoul National University Hospital, and review of the literature. | |
| G. Kim | |
| S. J. Lee | |
| H. P. Lee | |
| C. G. Yoo | |
| S. K. Han | |
| Y. S. Shim | |
| Y. W. Kim | |
| Department of Internal Medicine, Seoul National University College of Medicine and Lung Institute, SNUMRC, Korea. |
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