Document Detail

The clinical and biochemical effects of propofol infusion with and without EDTA for maintenance anesthesia in healthy children undergoing ambulatory surgery.
MedLine Citation:
PMID:  11429349     Owner:  NLM     Status:  MEDLINE    
IMPLICATIONS: The addition of EDTA does not alter the clinical profile of propofol in pediatric ambulatory surgical patients. With or without EDTA, propofol is associated with a decrease in ionized calcium with no apparent clinical effect.
I T Cohen; R S Hannallah; D B Goodale
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  93     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-06-28     Completed Date:  2001-07-19     Revised Date:  2014-07-28    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  106-11     Citation Subset:  AIM; IM    
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MeSH Terms
Ambulatory Surgical Procedures*
Anesthesia Recovery Period
Anesthesia, Intravenous*
Anesthetics, Intravenous / administration & dosage,  adverse effects*
Calcium / blood
Chelating Agents / adverse effects*
Child, Preschool
Double-Blind Method
Edetic Acid / adverse effects*
Hemodynamics / drug effects
Homeostasis / drug effects
Infusions, Intravenous
Kidney Function Tests
Monitoring, Intraoperative
Propofol / administration & dosage,  adverse effects*
Water-Electrolyte Balance / drug effects
Reg. No./Substance:
0/Anesthetics, Intravenous; 0/Chelating Agents; 9G34HU7RV0/Edetic Acid; SY7Q814VUP/Calcium; YI7VU623SF/Propofol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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