Document Detail

The circadian clock-associated small GTPase LIGHT INSENSITIVE PERIOD1 suppresses light-controlled endoreplication and affects tolerance to salt stress in Arabidopsis.
MedLine Citation:
PMID:  23144185     Owner:  NLM     Status:  MEDLINE    
Circadian clocks are biochemical timers regulating many physiological and molecular processes according to the day/night cycle. The small GTPase LIGHT INSENSITIVE PERIOD1 (LIP1) is a circadian clock-associated protein that regulates light input to the clock. In the absence of LIP1, the effect of light on free-running period length is much reduced. Here, we show that in addition to suppressing red and blue light-mediated photomorphogenesis, LIP1 is also required for light-controlled inhibition of endoreplication and tolerance to salt stress in Arabidopsis (Arabidopsis thaliana). We demonstrate that in the processes of endoreplication and photomorphogenesis, LIP1 acts downstream of the red and blue light photoreceptors phytochrome B and cryptochromes. Manipulation of the subcellular distribution of LIP1 revealed that the circadian function of LIP1 requires nuclear localization of the protein. Our data collectively suggest that LIP1 influences several signaling cascades and that its role in the entrainment of the circadian clock is independent from the other pleiotropic effects. Since these functions of LIP1 are important for the early stages of development or under conditions normally experienced by germinating seedlings, we suggest that LIP1 is a regulator of seedling establishment.
Kata Terecskei; Réka Tóth; Péter Gyula; Eva Kevei; János Bindics; George Coupland; Ferenc Nagy; László Kozma-Bognár
Related Documents :
23604485 - Light and the human circadian clock.
20033745 - Analysis of impulse adaptation in motoneurons.
8930285 - Reliability of spike propagation in arborizations of dorsal root fibers studied by anal...
3556485 - Neuronal coding of linear motion in the vestibular nuclei of the alert cat. i. response...
18811865 - Non-invasive diagnostic evaluation of phototherapeutic effects of red light phototherap...
24349685 - Effects of retinal position on the visuo-motor adaptation of visual stability in a virt...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-11-08
Journal Detail:
Title:  Plant physiology     Volume:  161     ISSN:  1532-2548     ISO Abbreviation:  Plant Physiol.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-31     Completed Date:  2013-06-18     Revised Date:  2014-01-09    
Medline Journal Info:
Nlm Unique ID:  0401224     Medline TA:  Plant Physiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  278-90     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Active Transport, Cell Nucleus
Arabidopsis / enzymology*,  genetics,  radiation effects
Arabidopsis Proteins / genetics,  metabolism*
Cell Nucleus / enzymology,  genetics
Cell Shape
Circadian Clocks*
Cotyledon / metabolism,  radiation effects,  ultrastructure
Cryptochromes / genetics,  metabolism
Genetic Complementation Test
Genetic Pleiotropy
Microscopy, Electron, Scanning
Monomeric GTP-Binding Proteins / genetics,  metabolism*
Photoreceptors, Plant / genetics,  metabolism
Phytochrome B / genetics,  metabolism
Recombinant Fusion Proteins / genetics,  metabolism
Salt-Tolerant Plants / enzymology,  genetics,  radiation effects
Sodium Chloride / pharmacology
Stress, Physiological*
Reg. No./Substance:
0/Arabidopsis Proteins; 0/CRY1 protein, Arabidopsis; 0/Cryptochromes; 0/PHYB protein, Arabidopsis; 0/Photoreceptors, Plant; 0/Recombinant Fusion Proteins; 136250-22-1/Phytochrome B; 7647-14-5/Sodium Chloride; EC small GTPase, Arabidopsis; EC GTP-Binding Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Cysteine-generated sulfide in the cytosol negatively regulates autophagy and modulates the transcrip...
Next Document:  Deficiency in a very-long-chain fatty acid ?-ketoacyl-coenzyme a synthase of tomato impairs microgam...