Document Detail


The chronic toxicity of sodium bicarbonate, a major component of coal bed natural gas produced waters.
MedLine Citation:
PMID:  24504936     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Sodium bicarbonate (NaHCO3 ) is the principal salt in coal bed natural gas produced water from the Powder River Structural Basin, Wyoming, USA, and concentrations of up to 3000 mg NaHCO3 /L have been documented at some locations. No adequate studies have been performed to assess the chronic effects of NaHCO3 exposure. The present study was initiated to investigate the chronic toxicity and define sublethal effects at the individual organism level to explain the mechanisms of NaHCO3 toxicity. Three chronic experiments were completed with fathead minnows (Pimephales promelas), 1 with white suckers (Catostomus commersoni), 1 with Ceriodaphnia dubia, and 1 with a freshwater mussel, (Lampsilis siliquoidea). The data demonstrated that approximately 500 mg NaHCO3 /L to 1000 mg NaHCO3 /L affected all species of experimental aquatic animals in chronic exposure conditions. Freshwater mussels were the least sensitive to NaHCO3 exposure, with a 10-d inhibition concentration that affects 20% of the sample population (IC20) of 952 mg NaHCO3 /L. The IC20 for C. dubia was the smallest, at 359 mg NaHCO3 /L. A significant decrease in sodium-potassium adenosine triphosphatase (Na(+) /K(+) ATPase) together with the lack of growth effects suggests that Na(+) /K(+) ATPase activity was shut down before the onset of death. Several histological anomalies, including increased incidence of necrotic cells, suggested that fish were adversely affected as a result of exposure to >450 mg NaHCO3 /L. Environ Toxicol Chem 2014;33:XX-XX. © 2014 SETAC. This article is a U.S. Government work and is in the public domain in the USA.
Authors:
Aïda M Farag; David D Harper
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-2-6
Journal Detail:
Title:  Environmental toxicology and chemistry / SETAC     Volume:  -     ISSN:  1552-8618     ISO Abbreviation:  Environ. Toxicol. Chem.     Publication Date:  2014 Feb 
Date Detail:
Created Date:  2014-2-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8308958     Medline TA:  Environ Toxicol Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2014 SETAC.
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