Document Detail


The chronic toxicity of methiocarb to grackles, doves, and quail and reproductive effect in quail.
MedLine Citation:
PMID:  1203576     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Methiocarb (4-methylthio-3, 5-xylyl N-methyl carbamate, Mesurol, Bay (3744), a bird repellent, was fed in concentrations of 100 to 1,000 ppm to common grackles (Quiscalus quiscula), mourning doves (Zenaida macroura), and breeding pairs of coturnix quail (Coturnix coturnix) to investigate the possibility of cumulative intoxication. Although aversion to treated diets was readily apparent in most of the tests, the 28- to 30-day median lethal concentration (LC50) was determined to be greater than 100 ppm for grackles, 630 ppm (95% confidence limits, 480-830 ppm) for doves, and greater than 1,000 ppm for coturnix quail. Methiocarb appeared to be noncumulative when measured by an index of chronicity: birds consumed several LD50 doses during a day's feeding, and when deaths occurred, they appeared to be due to acute intoxication. Egg production and live chick production were not affected in coturnix fed 100 ppm but were reduced at 316 and 1,000 ppm.
Authors:
E W Schafer; R B Brunton; N F Lockyer; D J Cunningham
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bulletin of environmental contamination and toxicology     Volume:  14     ISSN:  0007-4861     ISO Abbreviation:  Bull Environ Contam Toxicol     Publication Date:  1975 Dec 
Date Detail:
Created Date:  1976-03-30     Completed Date:  1976-03-30     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0046021     Medline TA:  Bull Environ Contam Toxicol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  641-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Birds / physiology*
Body Weight / drug effects
Coturnix / physiology*
Feeding Behavior / drug effects
Female
Fertility / drug effects
Insecticides / toxicity*
Male
Methiocarb / pharmacology,  toxicity*
Quail / physiology*
Reproduction / drug effects*
Species Specificity
Chemical
Reg. No./Substance:
0/Insecticides; 2032-65-7/Methiocarb

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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