| The choice of controls for providing validity and evidence in clinical research. | |
| | |
MedLine Citation:
|
PMID: 23018705 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Selection of controls, a group of subjects who are identical to the treatment group in all aspects that affect the outcome except the intervention of interest, is a significant criterion for conducting a study in evidence-based medical research. Few studies emphasize the appropriate selection of control groups in the plastic surgery literature. METHODS: The authors performed a literature search in Plastic and Reconstructive Surgery from January 1, 2010, through December 31, 2011, for studies in which controls were needed. The number of studies using a control group, control selection criteria, and the characteristics of the control populations were evaluated. RESULTS: Three hundred twenty-seven articles were obtained from our search using the keywords "case control studies" and "retrospective cohort studies." Among these studies, 121 articles were studies conducted in humans. All of these studies based on the study design required a control group, yet only 63 studies (52 percent) had a comparative control group. Of these studies, the authors found biases regarding the choice of controls, including selection bias, misclassification bias, and chronology bias. CONCLUSIONS: The authors' review shows that 48 percent of the studies published in Plastic and Reconstructive Surgery that were required to have a control group failed to incorporate a well-defined control group. Specific details pertaining to the methods used and the success obtained with those methods in recruiting controls need to be stated explicitly in the article to ensure uniformity and to support the validity of the research. |
| | |
Authors:
|
Sunitha Malay; Kevin C Chung |
Related Documents
:
|
11902425 - The use of auto-titrating continuous positive airway pressure for treatment of adult ob... 12712395 - Changes in depressive symptoms after continuous positive airway pressure treatment for ... 23177515 - Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after ... 23186315 - Emerging drugs for myelofibrosis. 11960085 - Caregiver burden in recent-onset schizophrenia and spectrum disorders: the influence of... 21835595 - Duration of untreated illness in schizophrenia is not associated with 5-year brain volu... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Review |
Journal Detail:
|
Title: Plastic and reconstructive surgery Volume: 130 ISSN: 1529-4242 ISO Abbreviation: Plast. Reconstr. Surg. Publication Date: 2012 Oct |
Date Detail:
|
Created Date: 2012-09-28 Completed Date: 2012-12-14 Revised Date: 2013-04-16 |
Medline Journal Info:
|
Nlm Unique ID: 1306050 Medline TA: Plast Reconstr Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 959-65 Citation Subset: AIM; IM |
Affiliation:
|
Section of Plastic Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, Mich. 48109-0340, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Biomedical Research* Case-Control Studies* Control Groups* Female Humans Male Patient Selection* Reconstructive Surgical Procedures / methods* Reference Values Reproducibility of Results Research Design |
| Grant Support | |
ID/Acronym/Agency:
|
2R01 AR047328-06/AR/NIAMS NIH HHS; K24 AR053120/AR/NIAMS NIH HHS; K24 AR053120/AR/NIAMS NIH HHS; R01 AR047328/AR/NIAMS NIH HHS; R01 AR062066/AR/NIAMS NIH HHS; R01 AR062066/AR/NIAMS NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bariatric surgery for the management of obesity: state of the field.
Next Document: Contradicting an established mantra: microsurgeon experience determines free flap outcome.