Document Detail


The chemistry and biology of LL-37.
MedLine Citation:
PMID:  19936387     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
LL-37 is a human host defence peptide that has a wide range of biological functions, including antimicrobial and immunomodulatory properties. This review summarises how molecular structure influences the balance between the immunomodulatory and antimicrobial functions of LL-37.
Authors:
Matthew F Burton; Patrick G Steel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2009-10-01
Journal Detail:
Title:  Natural product reports     Volume:  26     ISSN:  1460-4752     ISO Abbreviation:  Nat Prod Rep     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-25     Completed Date:  2009-12-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8502408     Medline TA:  Nat Prod Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  1572-84     Citation Subset:  IM    
Affiliation:
Centre for Bioactive Chemistry, Department of Chemistry, University of Durham, Science Laboratory, South Road, Durham, DH1 3LE, UK. m.f.burton@durham.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Amino Acid Sequence
Antimicrobial Cationic Peptides*
Humans
Molecular Sequence Data
Grant Support
ID/Acronym/Agency:
//Medical Research Council
Chemical
Reg. No./Substance:
0/Antimicrobial Cationic Peptides; 143108-26-3/CAP18 lipopolysaccharide-binding protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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