| The characteristics of concomitant thyroid nodules cause false-positive ultrasonography results in primary hyperparathyroidism. | |
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MedLine Citation:
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PMID: 19563934 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Concomitant thyroid nodules are the most common reason for false-positive ultrasonography (US) results in primary hyperparathyroidism. The aims of this prospective clinical study were to evaluate false-positive US results according to the characteristics of concomitant thyroid nodules and to determine which characteristics of thyroid nodules are important. STUDY DESIGN: This prospective study included 120 consecutive patients with primary hyperparathyroidism. The patients were divided into 2 groups according to preoperative US results. Group 1 consisted of 32 patients with false-positive US results and group 2 consisted of 88 patients with true-positive US results. RESULTS: The risk for false-positive US result was increased 25-fold for patients with parathyroid adenoma weight of more than 500 mg (odds ratio [OR], 25; 95% confidence interval [CI], 8.6-74.5), 75-fold for more than 1 posteriorly located thyroid (OR, 75; 95% CI, 19.3-293.4), 358-fold for the presence of exophytic thyroid nodules (OR, 358; 95% CI, 42.3-3036), and 423-fold for the presence of posteriorly located thyroid nodules (OR, 423; 95% CI, 49-3662). CONCLUSION: Although there was no particular characteristic of concomitant thyroid nodules that contributes to false-positive US results, the posteriorly located thyroid nodules were the strongest correlate for the false-positive US results to other features. |
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Authors:
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Umut Barbaros; Yeşim Erbil; Artür Salmashoğlu; Halim Işsever; Ferihan Aral; Mehtap Tunaci; Selçuk Ozarmağan |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2009-02-06 |
Journal Detail:
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Title: American journal of otolaryngology Volume: 30 ISSN: 1532-818X ISO Abbreviation: Am J Otolaryngol Publication Date: 2009 Jul-Aug |
Date Detail:
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Created Date: 2009-06-30 Completed Date: 2009-09-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8000029 Medline TA: Am J Otolaryngol Country: United States |
Other Details:
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Languages: eng Pagination: 239-43 Citation Subset: IM |
Affiliation:
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Department of Surgery, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Biopsy, Fine-Needle Diagnosis, Differential False Positive Reactions Female Follow-Up Studies Humans Hyperparathyroidism, Primary / complications, surgery, ultrasonography* Male Middle Aged Parathyroid Glands / pathology, ultrasonography Parathyroidectomy / methods Prognosis Prospective Studies Thyroid Gland / pathology, ultrasonography Thyroid Nodule / complications, surgery, ultrasonography* Thyroidectomy / methods Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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