Document Detail


The changing risk of infant mortality by gestation, plurality, and race: 1989-1991 versus 1999-2001.
MedLine Citation:
PMID:  17142535     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Our aim was to quantify contemporary infant mortality risks and to evaluate the change by plurality, gestation, and race during the most recent decade.
PATIENTS AND METHODS: The study population included live births of 20 to 43 weeks' gestation from the 1989-1991 and 1999-2001 US Birth Cohort Linked Birth/Infant Death Data Sets, including 11,317,895 and 11,181,095 live births and 89,823 and 67,129 infant deaths, respectively. Adjusted odds ratios and 95% confidence intervals were calculated to evaluate the change in risk by plurality and gestation and to compare the change with that for singletons.
RESULTS: Overall, the infant mortality risk decreased significantly for singletons, twins, and triplets but nonsignificantly for quadruplets and quintuplets. Compared with singletons, significantly greater reductions were experienced by twins overall and at <37 weeks and triplets at <29 weeks. The largest reduction was for triplets at 20 to 24 weeks and for quadruplets and quintuplets at 25 to 28 weeks. For white infants, significant reductions were achieved overall for singletons, twins, and triplets and at every gestation. For black infants, significant reductions occurred for singletons overall and at every gestation, for twins at <37 weeks, and for triplets at 25 to 28 weeks. Compared with white infants, black infants had significantly lower risks before and higher risks after 33 weeks, although between 1989-1991 and 1999-2001 this survival advantage at earlier ages diminished, and the risk at later gestations increased.
CONCLUSIONS: The improvements in survival were greater for multiples versus singletons and for white versus black infants. Within each plurality, at each gestation the racial disparity in mortality has widened.
Authors:
Barbara Luke; Morton B Brown
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Pediatrics     Volume:  118     ISSN:  1098-4275     ISO Abbreviation:  Pediatrics     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-12-04     Completed Date:  2006-12-19     Revised Date:  2013-06-06    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2488-97     Citation Subset:  AIM; IM    
Affiliation:
School of Nursing and Health Studies, University of Miami, 5801 Red Rd, Coral Gables, FL, USA. bluke@med.miami.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
African Continental Ancestry Group
European Continental Ancestry Group
Gestational Age
Humans
Infant Mortality / trends*
Infant, Newborn
Quadruplets
Quintuplets
Risk Factors
Triplets
Twins
Grant Support
ID/Acronym/Agency:
R03 HD047627/HD/NICHD NIH HHS; R03 HD047627/HD/NICHD NIH HHS; R03 HD048498/HD/NICHD NIH HHS; R03 HD048498/HD/NICHD NIH HHS
Comments/Corrections

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