Document Detail


A changing perspective: improving access to fertility preservation.
MedLine Citation:
PMID:  20736926     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Approximately 120,000 young women are diagnosed with cancer every year in the USA. Many will have treatment that can reduce their fertility, although few will learn this fact before their treatment commences. This presents a tremendous quality of life issue post-treatment, as evidenced in this Perspectives by a personal account from a 23-year-old woman diagnosed with breast cancer. Clinicians must increase awareness about patients' desires for motherhood and awareness about their individual reproductive potential. We demonstrate novel evidence about the wide variability in ovarian reserve in women of similar age, using assessment by antral follicle count. We show how a unified approach between oncology and fertility teams can help patients better understand their risk of treatment-related infertility, as well as how to take effective measures to mitigate it. Finally, we present options for fertility preservation, based on the time point at which consultation occurs.
Authors:
Joseph M Letourneau; Michelle E Melisko; Marcelle I Cedars; Mitchell P Rosen
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2010-08-24
Journal Detail:
Title:  Nature reviews. Clinical oncology     Volume:  8     ISSN:  1759-4782     ISO Abbreviation:  Nat Rev Clin Oncol     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-23     Completed Date:  2011-04-12     Revised Date:  2013-05-28    
Medline Journal Info:
Nlm Unique ID:  101500077     Medline TA:  Nat Rev Clin Oncol     Country:  England    
Other Details:
Languages:  eng     Pagination:  56-60     Citation Subset:  IM    
Affiliation:
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco School of Medicine, 94143, USA. joseph.letourneau@ucsf.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Breast Neoplasms / physiopathology*
Carcinoma, Ductal, Breast / physiopathology*
Family Planning Services
Female
Humans
Infertility, Female / etiology,  therapy*
Pregnancy
Pregnancy Complications, Neoplastic*
Tissue Preservation*
Young Adult
Grant Support
ID/Acronym/Agency:
R01 HD044876/HD/NICHD NIH HHS; R01 HD044876-02/HD/NICHD NIH HHS; UL1 RR024131/RR/NCRR NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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