Document Detail

The changing face of mesenteric infarction.
MedLine Citation:
PMID:  9655269     Owner:  NLM     Status:  MEDLINE    
Intestinal infarction remains a devastating event despite improvements in clinical recognition as well as diagnostic and therapeutic modalities. Recent changes in the etiology of this disease have not been examined. A retrospective review of 121 consecutive patients over a 6-year period was undertaken. Twenty-three patients died without operation, and mortality in the remaining 98 patients was 50 per cent. The only significant predictor of mortality was an elevated serum lactate at the time of diagnosis. Thirty-one patients (26%) developed infarction while hospitalized for another disease process; excluding patients with obstruction as the etiology of infarction caused this number to rise to 39 per cent. Nonocclusive mesenteric infarction was the most common disease process. The increased incidence of nonocclusive mesenteric infarction is likely due to the development of intestinal ischemia in already systemically ill patients. Nearly half of all cases of intestinal infarction due to nonobstructive causes develop in already hospitalized patients. The development of unexplained acidosis in a postoperative or critically ill patient should prompt a search for a reversible cause of mesenteric ischemia. Intestinal infarction may represent another example of the multisystem organ failure syndrome.
T S Newman; T H Magnuson; S A Ahrendt; M A Smith-Meek; J S Bender
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American surgeon     Volume:  64     ISSN:  0003-1348     ISO Abbreviation:  Am Surg     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-07-23     Completed Date:  1998-07-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370522     Medline TA:  Am Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  611-6     Citation Subset:  IM    
Department of Surgery, Johns Hopkins Bayview Medical Center, Baltimore, Maryland 21224, USA.
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MeSH Terms
Case-Control Studies
Infarction / diagnosis,  epidemiology*,  etiology,  surgery
Intestines / blood supply*
Mesenteric Vascular Occlusion / diagnosis,  epidemiology*,  etiology,  surgery
Middle Aged
Retrospective Studies
Risk Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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