Document Detail


The challenge of maternal phenylketonuria screening and treatment.
MedLine Citation:
PMID:  2198347     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
All newborn infants, male and female, have been screened for phenylketonuria (PKU) since 1961. Medical therapy is generally continued until age 6. The first cohort of treated females reached reproductive age 15 years ago, and new members are joining this cohort annually. This paper reviews the implications of childbearing in women who were treated for PKU as children and are no longer under treatment. Untreated maternal PKU can lead to mental retardation in utero.
Authors:
B Luke; L G Keith
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  35     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  1990 Jul 
Date Detail:
Created Date:  1990-09-05     Completed Date:  1990-09-05     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  667-73     Citation Subset:  IM    
Affiliation:
Department of Gynecology and Obstetrics, Johns Hopkins University, School of Medicine, Baltimore, MD 21205.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Female
Humans
Mass Screening / organization & administration*,  standards
Phenylketonurias / genetics,  physiopathology,  prevention & control*
Pregnancy
Pregnancy Complications / prevention & control*

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