Document Detail


The central vein access port and catheter in outpatient chemotherapy for colorectal cancer: a retrospective study of 101 patients.
MedLine Citation:
PMID:  22105529     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: The central venous access port (CV-port) system was examined in a series of colorectal cancer (CRC) patients. METHODS: One hundred and one CRC patients underwent chemotherapy with the 5-fluorouracil + oxaliplatin (FOLFOX) or 5-fluorouracil + irinotecan regimen. The complications of the CV-port system were retrospectively assessed. RESULTS: The CV-port system was placed in a total of 101 patients. The patients received a total of 1035 courses of these regimens. Eight complications occurred in the 101 patients (7.9%). The complications included three instances of catheter rupture, two thrombotic events around the catheter, and three infections at the site of the port or catheter. The complications were identified after a median of nine courses (range 6-16) and 135 days after the placement of the CV-port system. Sixty-six of the 101 patients switched their regimen from FOLFOX to another regimen, and 4 of these 66 patients (6.1%) experienced complications associated with the CV-port system. There were 25 subjects who were admitted to the hospital emergency wing during the chemotherapeutic regimens, and 4 of these patients (16%) had complications associated with the CV-port system. CONCLUSIONS: The complications of the CV-port system occurred at a defined rate, therefore the early diagnosis and the appropriate treatment to address these complications is crucial.
Authors:
Hiroshi Sawayama; Naoko Hayashi; Masayuki Watanabe; Hiroshi Takamori; Toru Beppu; Hideo Baba
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-22
Journal Detail:
Title:  Surgery today     Volume:  -     ISSN:  1436-2813     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204360     Medline TA:  Surg Today     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan.
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